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Invitrogen
OLFM4 Monoclonal Antibody (12)
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Application
FIGURE: 1 / 1
OLFM4 Antibody (MA5-29457) in Flow
Flow cytometric analysis of Human OLFM4 expression in DU145 cells. The cells were treated according to manufacturer’s manual, and stained with OLFM4 Monoclonal Antibody (12) (Product # MA5-29457), then a FITC-conjugated Secondary antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Product Details
MA5-29457
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
12
Immunogen
Recombinant Human OLFM4/GW112 protein (Met1-Gln510)
Conjugate
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Purification
Protein A
Storage buffer
PBS with 10% trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785318
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human OLFM4/GW112.
Target Information
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; Olfactomedin-4; OLM4
Gene Aliases: bA209J19.1; GC1; GW112; hGC-1; hOLfD; OlfD; OLFM4; OLM4; UNQ362; UNQ362/PRO698
UniProt ID: (Human) Q6UX06
Entrez Gene ID: (Human) 10562
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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