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Invitrogen
OSCAR Monoclonal Antibody (C2)
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Product Details
MA5-43634
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C2
Immunogen
Polypeptide conjugated human OVA. The polypeptide sequence is Pyr-Gly95-Pro109.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2912566
Target Information
Recently, a novel member of the leukocyte receptor complex (LRC) encoded family has been identified that is expressed specifically in osteoclast (OC). This protein names OC-associated receptor or OSCAR, play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation. Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This protein family plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC33613; osteoclast associated receptor OSCAR-S1; osteoclast associated receptor OSCAR-S2; Osteoclast-associated immunoglobulin-like receptor; Osteoclast-associated receptor; PIgR-3; poly-Ig receptor 3; Polymeric immunoglobulin receptor 3
Gene Aliases: OSCAR; PIgR-3; PIGR3
UniProt ID: (Human) Q8IYS5
Entrez Gene ID: (Human) 126014
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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