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Application
FIGURE: 1 / 5
OTOF Antibody (PA5-52935) in IHC (P)
Immunohistochemical analysis of OTOF in human prostate using OTOF Polyclonal Antibody (Product # PA5-52935) shows no positivity in glandular cells as expected.
Product Details
PA5-52935
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human OTOF. Recombinant protein control fragment (Product #RP-90139).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2645105
Product Specific Information
Immunogen sequence: PIIVIEIYDQ DSMGKADFMG RTFAKPLVKM ADEAYCPPRF PPQLEYYQIY RGNATAGDLL AAFELLQIGP AGKADLPPIN GPVDVDRGPI MPVPMGIRPV LSKYRVEVLF WGLRDLKRVN L
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
Target Information
Otoferlin is a protein that in humans is encoded by the OTOF gene. Mutations in this gene are a cause of neurosensory nonsyndromic recessive deafness, DFNB9. The short form of the encoded protein has three C2 domains, a single carboxy-terminal transmembrane domain found also in the C. elegans spermatogenesis factor FER-1 and human dysferlin, while the long form has six C2 domains. The homology suggests that this protein may be involved in vesicle membrane fusion. Several transcript variants encoding multipleisoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: fer-1-like family member 2; Fer-1-like protein 2; Otoferlin
Gene Aliases: AUNB1; DFNB6; DFNB9; FER1L2; NSRD9; OTOF
UniProt ID: (Human) Q9HC10
Entrez Gene ID: (Human) 9381
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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