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Proteintech
OXT Polyclonal Antibody
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Application
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OXT Antibody (18041-1-AP) in IHC (P)
Immunohistochemical analysis of paraffin-embedded human pituitary tissue slide using (Product # 18041-1-AP) (OXT antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).
Product Details
18041-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OXT Fusion Protein Ag12672
Conjugate
Unconjugated
Form
Liquid
Concentration
180 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: neurophysin 1; neurophysin I; OT-NPI; oxcytocin; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; Oxytocin-neurophysin 1; oxytocin-neurophysin I, preproprotein; oxytocin/neurophysin (Oxt) gene, complete gene, complete cds
Gene Aliases: OT; OT-NPI; OXT; OXT-NPI; Oxy
UniProt ID: (Human) P01178, (Mouse) P35454, (Rat) P01179
Entrez Gene ID: (Human) 5020, (Mouse) 18429, (Rat) 25504
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