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This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
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Protein Aliases: FLJ12296; matrin type 3; MGC10613; p53 target zinc finger protein; p53-activated gene 608 protein; WIG-1/PAG608 protein; wild-type p53-induced gene 1; wild-type p53-induced gene 1 protein; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; zinc finger protein WIG1; zmat3; zmat3 {ECO:0000250|UniProtKB:Q9HA38}
Gene Aliases: PAG608; WIG-1; WIG1; ZMAT3
UniProt ID: (Human) Q9HA38, (Rat) O08781
Entrez Gene ID: (Human) 64393, (Rat) 64394, (Mouse) 22401
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