Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 1
Immunogen sequence: HHCAPRRGRR LLLSRVFQPQ NLREDRVLSL QDKSDDLTCK SQRLMLQVGL IYPASPGCYH LLPYTVRAME KLVRVIDQEM QAIGGQKVNM PSLSPAELWQ ATNRWDLMGK ELLRLRDRHG KEYCLGPTHE EAITALIASQ KKLSYKQLPF LLYQVTRKFR DEPRPRFGLL RGREFYMKDM YTFDSSPEAA Q; Positive Samples: Rat brain; Cellular Location: Mitochondrion matrix
This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of proline to tRNA molecules. Mutations have been found in this gene in some patients with Alpers syndrome. [provided by RefSeq, Mar 2015]
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Protein Aliases: Probable proline--tRNA ligase, mitochondrial; probable prolyl-tRNA synthetase, mitochondrial; proline--tRNA ligase; Prolyl-tRNA synthetase; prolyl-tRNA synthetase (mitochondrial)(putative); ProRS
Gene Aliases: Pars2; RGD1305345
UniProt ID: (Rat) Q5M7W7
Entrez Gene ID: (Rat) 313429
Molecular Function:
aminoacyl-tRNA synthetase
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