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PAX7 Polyclonal Antibody

PAX7 Antibody in Immunocytochemistry (ICC/IF)

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PAX7 Antibody (20570-1-AP) in ICC/IF

Immunofluorescent analysis of ( 4% PFA) fixed MCF-7 cells using 20570-1-AP (PAX7 antibody) at dilution of 1:50 and Alexa Fluor 488-Conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

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Product Details

20570-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:500

View 9 publications 9 publications

Not applicable (N/A)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Not Applicable

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.45 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody is specific to PAX7. It will not cross react with other PAX members.

Target Information

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Urotensin II can Induce Skeletal Muscle Atrophy Associated with Upregulating Ubiquitin-Proteasome System and Inhibiting the Differentiation of Satellite Cells in CRF Mice.

Calcified tissue international

Pan Y,Zhou T,Dong X,Wu L,Wang P,Wang S,Zhang A

Mon May 01 00:00:00 UTC 2023

A Novel in Duck Myoblasts: The Transcription Factor Retinoid X Receptor Alpha (RXRA) Inhibits Lipid Accumulation by Promoting CD36 Expression.

International journal of molecular sciences

Pan Z,Chen X,Wu D,Li X,Gao W,Li G,Du G,Zhang C,Jin S,Geng Z

Sat Jan 07 00:00:00 UTC 2023

TGM2 positively regulates myoblast differentiation via enhancing the mTOR signaling.

Biochimica et biophysica acta. Molecular cell research

Wang D,Zhao D,Li Y,Dai T,Liu F,Yan C

Tue Mar 01 00:00:00 UTC 2022

Myoblast-derived exosomes promote the repair and regeneration of injured skeletal muscle in mice.

FEBS open bio

Ji S,Ma P,Cao X,Wang J,Yu X,Luo X,Lu J,Hou W,Zhang Z,Yan Y,Dong Y,Wang H

Thu Dec 01 00:00:00 UTC 2022

Myoblast-derived exosomes promote the repair and regeneration of injured skeletal muscle in mice.

FEBS open bio

Ji S,Ma P,Cao X,Wang J,Yu X,Luo X,Lu J,Hou W,Zhang Z,Yan Y,Dong Y,Wang H

Thu Dec 01 00:00:00 UTC 2022

Apolipoprotein H: a novel regulator of fat accumulation in duck myoblasts.

Journal of animal science and technology

Pan Z,Du G,Li G,Wu D,Chen X,Geng Z

Tue Nov 01 00:00:00 UTC 2022

Role of lncRNA Has2os in Skeletal Muscle Differentiation and Regeneration.

Cells

Chen W,Chen W,Liu P,Qian S,Tao S,Huang M,Xu W,Li C,Chen X,Lin H,Qin Z,Lu J,Xie S

Fri Nov 04 00:00:00 UTC 2022

circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop.

Journal of cachexia, sarcopenia and muscle

Yan J,Yang Y,Fan X,Liang G,Wang Z,Li J,Wang L,Chen Y,Adetula AA,Tang Y,Li K,Wang D,Tang Z

Tue Feb 01 00:00:00 UTC 2022

CircUBE2Q2 promotes differentiation of cattle muscle stem cells and is a potential regulatory molecule of skeletal muscle development.

BMC genomics

Zhang RM,Pan Y,Zou CX,An Q,Cheng JR,Li PJ,Zheng ZH,Pan Y,Feng WY,Yang SF,Shi DS,Wei YM,Deng YF

Wed Apr 06 00:00:00 UTC 2022

Time-Series Clustering of lncRNA-mRNA Expression during the Adipogenic Transdifferentiation of Porcine Skeletal Muscle Satellite Cells.

Current issues in molecular biology

Qiu X,Gao G,Du L,Wang J,Wang Q,Yang F,Zhou X,Long D,Huang J,Liu Z,Qi R

Fri May 06 00:00:00 UTC 2022

PERK Signaling Controls Myoblast Differentiation by Regulating MicroRNA Networks.

Frontiers in cell and developmental biology

Tan YY,Zhang Y,Li B,Ou YW,Xie SJ,Chen PP,Mei SQ,Huang QJ,Zheng LL,Qu LH

Tue Jun 15 00:00:00 UTC 2021

Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.

Theranostics

Guo S,Meng L,Liu H,Yuan L,Zhao N,Ni J,Zhang Y,Ben J,Li YP,Ma J

Thu Jul 29 00:00:00 UTC 2021

Trio cooperates with Myh9 to regulate neural crest-derived craniofacial development.

Theranostics

Guo S,Meng L,Liu H,Yuan L,Zhao N,Ni J,Zhang Y,Ben J,Li YP,Ma J

Thu Jul 29 00:00:00 UTC 2021

Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.

Journal of extracellular vesicles

Gao X,Wang Y,Lu F,Chen X,Yang D,Cao Y,Zhang W,Chen J,Zheng L,Wang G,Fu M,Ma L,Song Y,Zhan Q

Mon Mar 01 00:00:00 UTC 2021

Overexpression of Dnmt3a ameliorates diabetic muscle atrophy by modulating the Pten/Akt pathway.

Experimental physiology

Wang M,Wu X,Gan L,Teng Z,Zhang H,Zhang Y

Sun Nov 01 00:00:00 UTC 2020

Exosomes of oral squamous cell carcinoma cells containing miR-181a-3p induce muscle cell atrophy and apoptosis by transmissible endoplasmic reticulum stress signaling.

Biochemical and biophysical research communications

Qiu L,Chen W,Wu C,Yuan Y,Li Y

Thu Dec 17 00:00:00 UTC 2020

KLF2 in Myeloid Lineage Cells Regulates the Innate Immune Response during Skeletal Muscle Injury and Regeneration.

iScience

Manoharan P,Song T,Radzyukevich TL,Sadayappan S,Lingrel JB,Heiny JA

Fri Jul 26 00:00:00 UTC 2019

Dilated cardiomyopathy-mediated heart failure induces a unique skeletal muscle myopathy with inflammation.

Skeletal muscle

Song T,Manoharan P,Millay DP,Koch SE,Rubinstein J,Heiny JA,Sadayappan S

Thu Jan 24 00:00:00 UTC 2019

Anti-aging Effect of Transplanted Amniotic Membrane Mesenchymal Stem Cells in a Premature Aging Model of Bmi-1 Deficiency.

Scientific reports

Xie C,Jin J,Lv X,Tao J,Wang R,Miao D

Tue Sep 15 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: FLJ37460; HuP1; paired box gene 7; paired box homeotic gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A

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Gene Aliases: HUP1; Pax-7; PAX7; PAX7B; RMS2

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UniProt ID: (Human) P23759, (Mouse) P47239

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Entrez Gene ID: (Human) 5081, (Mouse) 18509

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Function(s)

transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding DNA binding protein binding

Process(es)

chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter multicellular organism development muscle organ development skeletal muscle tissue development organ morphogenesis regulation of cell fate commitment regulation of gene expression skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration positive regulation of transcription from RNA polymerase II promoter neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation anatomical structure morphogenesis negative regulation of apoptotic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PAX7 Polyclonal Antibody

PAX7 Antibody (20570-1-AP) in ICC/IF

Product Details

20570-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Not applicable (N/A)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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