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Invitrogen

PAX7 Polyclonal Antibody

2 Published Figures

7 References

View all (34) PAX7 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)
Published Figures (2)

Application

PAX7 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

PAX7 Antibody (PA5-68506) in ICC/IF

Immunofluorescent analysis of PAX7 in C2C12 cells using PAX7 polyclonal antibody (Product # PA5-68506).

PAX7 Antibody in Surface plasmon resonance (SPR)

PAX7 Antibody in Immunocytochemistry, Immunohistochemistry (ICC/IF, IHC)

Product Image Gallery

Product Details

PA5-68506

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

View 1 publication 1 publication

Immunohistochemistry (PFA fixed) (IHC (PFA))

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100

View 3 publications 3 publications

Surface plasmon resonance (SPR)

Assay-dependent

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Bovine, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the middle region of human PAX7

Conjugate

Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2688368

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Target Information

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Traditional Chinese Medicine for Topical Treatment of Skeletal Muscle Injury.

Pharmaceuticals (Basel, Switzerland)

Siu WS,Ma H,Cheng W,Shum WT,Leung PC

PA5-68506 was used in Immunohistochemistry to demonstrate that topical Carthami Flos, Dipsaci Radix, and Rhei Rhizoma (CDR) treatment was effective at facilitating muscle injury repair.

Sat Aug 12 00:00:00 UTC 2023

VEGFA Promotes Skeletal Muscle Regeneration in Aging.

Advanced biology

Endo Y,Hwang CD,Zhang Y,Olumi S,Koh DJ,Zhu C,Neppl RL,Agarwal S,Sinha I

PA5-68506 was used in Immunohistochemistry (Paraffin) to suggest that VEGFA may be a therapeutic target in age-related muscle loss.

Sun Oct 01 00:00:00 UTC 2023

Effects of Hypoxia on Proliferation and Differentiation in Belgian Blue and Hanwoo Muscle Satellite Cells for the Development of Cultured Meat.

Biomolecules

Park S,Gagliardi M,Swennen G,Dogan A,Kim Y,Park Y,Park G,Oh S,Post M,Choi J

Published figure using PAX7 polyclonal antibody (Product # PA5-68506) in Immunocytochemistry

Thu Jun 16 00:00:00 UTC 2022

Simple and effective serum-free medium for sustained expansion of bovine satellite cells for cell cultured meat.

Communications biology

Stout AJ,Mirliani AB,Rittenberg ML,Shub M,White EC,Yuen JSK,Kaplan DL

PA5-68506 was used in Immunocytochemistry-immunoflourescence to offer a simple, affordable, and effective Beefy-9 and Beefy-9+ serum-free media for improving cultured meat research.

Thu Jun 02 00:00:00 UTC 2022

Extracellular Heme Proteins Influence Bovine Myosatellite Cell Proliferation and the Color of Cell-Based Meat.

Foods (Basel, Switzerland)

Simsa R,Yuen J,Stout A,Rubio N,Fogelstrand P,Kaplan DL

PA5-68506 was used in Immunohistochemistry (PFA fixed) and Immunocytochemistry to indicate a potential benefit of adding Mb to cell culture media for increased proliferation and adding Mb or Hb for the coloration of cell-based meat.

Mon Oct 21 00:00:00 UTC 2019

Extracellular Heme Proteins Influence Bovine Myosatellite Cell Proliferation and the Color of Cell-Based Meat.

Foods (Basel, Switzerland)

Simsa R,Yuen J,Stout A,Rubio N,Fogelstrand P,Kaplan DL

Mon Oct 21 00:00:00 UTC 2019

Extracellular Heme Proteins Influence Bovine Myosatellite Cell Proliferation and the Color of Cell-Based Meat.

Foods (Basel, Switzerland)

Simsa R,Yuen J,Stout A,Rubio N,Fogelstrand P,Kaplan DL

Mon Oct 21 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: FLJ37460; HuP1; paired box gene 7; paired box homeotic gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A

Gene Aliases: HUP1; Pax-7; PAX7; PAX7B; RGD1564360; RMS2

UniProt ID: (Human) P23759, (Mouse) P47239

Entrez Gene ID: (Human) 5081, (Mouse) 18509, (Rat) 500574

Function(s)

transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, sequence-specific DNA binding sequence-specific DNA binding DNA binding protein binding

Process(es)

chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter multicellular organism development muscle organ development skeletal muscle tissue development organ morphogenesis regulation of cell fate commitment regulation of gene expression skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration positive regulation of transcription from RNA polymerase II promoter neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation anatomical structure morphogenesis negative regulation of apoptotic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PAX7 Polyclonal Antibody

PAX7 Antibody (PA5-68506) in ICC/IF

Product Details

PA5-68506

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Immunocytochemistry (ICC/IF)

Surface plasmon resonance (SPR)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Function(s)

Process(es)

Performance Guarantee

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