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Bioss

PBEF1 Polyclonal Antibody

View all (33) NAMPT antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)

Application

PBEF1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

PBEF1 Antibody (BS-0272R) in IHC (P)

Formalin-fixed and paraffin embedded human kidney labeled with Anti-PBEF1 Polyclonal Antibody, Unconjugated (bs-0272R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

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Product Details

BS-0272R

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500

Immunocytochemistry (ICC/IF)

1:50-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human PBEF, amino acids 301-400.

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DKFZp666B131; EC 2.4.2.12; MGC117256; NAmPRTase; Nicotinamide phosphoribosyltransferase; PBEF; Pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; Pre-B-cell colony-enhancing factor 1; Pre-B-cell colony-enhancing factor 1 homolog; Visfatin

Gene Aliases: 1110035O14Rik; AI314458; AI480535; NAmPRTase; NAMPT; PBEF; PBEF1; VF; VISFATIN

UniProt ID: (Human) P43490, (Mouse) Q99KQ4, (Rat) Q80Z29

Entrez Gene ID: (Human) 10135, (Mouse) 59027, (Rat) 297508

Function(s)

nicotinate-nucleotide diphosphorylase (carboxylating) activity cytokine activity protein binding drug binding protein homodimerization activity nicotinamide phosphoribosyltransferase activity transferase activity transferase activity, transferring glycosyl groups transferase

Process(es)

nicotinamide metabolic process signal transduction cell-cell signaling female pregnancy circadian rhythm positive regulation of cell proliferation insulin receptor signaling pathway NAD biosynthetic process response to organic cyclic compound circadian regulation of gene expression positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle cell proliferation positive regulation of nitric-oxide synthase biosynthetic process adipose tissue development pyridine nucleotide biosynthetic process rhythmic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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