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            • Primary Antibodies ›
            • PCDHGB2 Antibodies

            Invitrogen

            PCDHGB2 Polyclonal Antibody

            View all (8) PCDHGB2 antibodies
            Datasheet
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            Catalog # PA5-85036
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            Price (USD)
            498.00
            100 µL
             
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            Cite PCDHGB2 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            PCDHGB2 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            PCDHGB2 Antibody (PA5-85036) in ICC/IF

            Immunofluorecent analysis of PCDHGB2 in human cell line RH-30 using PCDHGB2 Polyclonal Antibody (Product # PA5-85036). Staining shows localization to plasma membrane, cytosol and vesicles.
            View Product

            PCDHGB2 Antibody in Immunocytochemistry (ICC/IF)

            Product Details

            PA5-85036

            Applications
            Tested Dilution
            Publications

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human PCDHGB2. Recombinant protein control fragment (Product #RP-108116).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.3 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2792185

            Product Specific Information

            Immunogen sequence: PLFKQTKINL KIGESTKPGT TFPLDPALDS DVGPNSLQRY HLNDNEYFDL AEKQTPDGRK YP

            Target Information

            This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: PCDH-gamma-B2; Protocadherin gamma-B2

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            Gene Aliases: PCDH-GAMMA-B2; PCDHGB2

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            UniProt ID: (Human) Q9Y5G2

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            Entrez Gene ID: (Human) 56103

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            Function(s)

            calcium ion binding cadherin

            Process(es)

            homophilic cell adhesion via plasma membrane adhesion molecules
            It has to be done as per old AB suggested Products section.
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