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In direct ELISAs, less than 20% cross-reactivity with recombinant human (rh) Proprotein Convertase 9 is observed, and less than 1% cross-reactivity with rhProprotein Convertase 1 and rhProprotein Convertase 7 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. The protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: convertase subtilisin; hypercholesterolemia; NARC-1; neural apoptosis regulated convertase 1; Neural apoptosis-regulated convertase 1; OTTHUMP00000009833; PC9; Proprotein convertase 9; proprotein convertase PC9; Proprotein convertase subtilisin/kexin type 9; Subtilisin/kexin-like protease PC9
Gene Aliases: AI415265; AI747682; FH3; HCHOLA3; NARC-1; Narc1; PC9; Pcsk9
UniProt ID: (Rat) P59996, (Mouse) Q80W65
Entrez Gene ID: (Rat) 298296, (Mouse) 100102
Molecular Function:
serine protease
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