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            • Primary Antibodies ›
            • PDE1C Antibodies

            Proteintech

            PDE1C Polyclonal Antibody

            2 References
            View all (12) PDE1C antibodies

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            Datasheet
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            Catalog # 13785-1-AP
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            Price (USD)
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            150 µL
             
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            Datasheet
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            Cite PDE1C Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            PDE1C Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            PDE1C Antibody (13785-1-AP) in WB

            Human heart tissue were subjected to SDS PAGE followed by western blot with 13785-1-AP (PDE1C antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.
            View Product

            PDE1C Antibody in Western Blot (WB)
            PDE1C Antibody in Immunoprecipitation (IP)

            Product Details

            13785-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            View 2 publications 2 publications

            Immunoprecipitation (IP)

            0.5-4.0 µg
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            PDE1C Fusion Protein Ag4798 (284-634 aa encoded by BC022525)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.21 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            Immunogen sequence: RSDPAILYN DRSVLENHHL SAAYRLLQDD EEMNILINLS KDDWREFRTL VIEMVMATDM SCHFQQIKAM KTALQQPEAI EKPKALSLML HTADISHPAK AWDLHHRWTM SLLEEFFRQG DREAELGLPF SPLCDRKSTM VAQSQVGFID FIVEPTFTVL TDMTEKIVSP LIDETSQTGG TGQRRSSLNS ISSSDAKRSG VKTSGSEGSA PINNSVISVD YKSFKATWTE VVHINRERWR AKVPKEEKAK KEAEEKARMA AEEQQKEMEA KSQAEEGASG KAEKKTSGET KNQVNGTRAN KSDNPRGKNS KAEKSSGEQQ QNGDFKDGKN KTDKKDHSNI GNDSKKTDDS QE (284-634 aa encoded by BC022525)

            Target Information

            Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; cyclic nucleotide phosphodiesterase 1 C; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Hcam3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C calmodulin-dependent (70kD); phosphodiesterase 1C, calmodulin-dependent 70kDa

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            Gene Aliases: cam-PDE 1C; hCam-3; Hcam3; PDE1C; Pde1c2

            View more View less

            UniProt ID: (Human) Q14123, (Mouse) Q64338, (Rat) Q63421

            View more View less

            Entrez Gene ID: (Human) 5137, (Mouse) 18575, (Rat) 81742

            View more View less

            Function(s)

            calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding metal ion binding 3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity phosphoric diester hydrolase activity hydrolase activity cAMP binding calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity phosphodiesterase

            Process(es)

            signal transduction cAMP catabolic process sensory perception of smell cGMP catabolic process negative regulation of insulin secretion response to calcium ion metabolic process
            It has to be done as per old AB suggested Products section.
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