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Rockland
PI4K beta Polyclonal Antibody
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Application
FIGURE: 1 / 1
PI4K beta Antibody (600-401-J92) in IHC (P)
Immunohistochemistry of Rabbit anti-PIK4CB / PI4KB antibody. Tissue: Liver. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: PIK4CB / PI4KB antibody at 5 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Staining: PIK4CB / PI4KB as precipitated red signal with hematoxylin purple nuclear counterstain.
Product Details
600-401-J92
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-PI4K beta affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human PI4K beta protein.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 40% glycerol, 0.15M NaCl
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
A BLAST analysis was used to suggest cross-reactivity with bat, rat, primate, mouse, and human based on 100% sequence homology. Cross-reactivity with PI4K beta from other sources has not been determined.
Target Information
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol. Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Target protein phosphorylates phosphatidylinositol (PtdIns) at the D4 position of the inositol ring; may play a role in neuronal differentiation and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NPIK; phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, wortmannin-sensitive; PI4K-beta; PI4K92; PI4KIII; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta
Gene Aliases: NPIK; PI4K-BETA; PI4K92; PI4KB; PI4KBETA; PI4KIIIBETA; PIK4CB
UniProt ID: (Human) Q9UBF8
Entrez Gene ID: (Human) 5298
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