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Invitrogen

PIN1 Polyclonal Antibody

View all (39) PIN1 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (5)

Application

PIN1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

PIN1 Antibody (PA5-35372) in ICC/IF

Immunocytochemistry analysis of PIN1 in 293 cells. Samples were incubated in PIN1 polyclonal antibody (Product # PA5-35372) followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

PIN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

PA5-35372

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

Immunocytochemistry (ICC/IF)

1:10-1:50

Flow Cytometry (Flow)

1:10-1:50

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide between 30-56 amino acids from the central region of human PIN1

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A, Antigen affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

0.09% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2552682

Product Specific Information

This antibody is predicted to react with non-human primate based on sequence homology.

Target Information

PIN1 (Peptidylprolyl Cis/Trans Isomerase, NIMA-Interacting 1) is a Protein Coding gene. Diseases associated with PIN1 include Meibomian Cyst and Viral Exanthem. Among its related pathways are Transport of the SLBP independent Mature mRNA and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and mitogen-activated protein kinase binding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EC 5.2.1.8; NIMA-interacting; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1; Peptidyl-prolyl cis-trans isomerase Pin1; PPIase Pin1; prolyl isomerase; protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1; Rotamase Pin1

Gene Aliases: DOD; PIN1; UBL5

UniProt ID: (Human) Q13526

Entrez Gene ID: (Human) 5300

Function(s)

peptidyl-prolyl cis-trans isomerase activity motor activity protein binding beta-catenin binding mitogen-activated protein kinase kinase binding GTPase activating protein binding phosphoserine binding phosphothreonine binding chaperone

Process(es)

protein peptidyl-prolyl isomerization positive regulation of protein phosphorylation cell cycle regulation of mitotic nuclear division neuron differentiation negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of protein binding regulation of cytokinesis negative regulation of type I interferon production positive regulation of protein dephosphorylation negative regulation of protein catabolic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process positive regulation of GTPase activity positive regulation of transcription from RNA polymerase II promoter synapse organization protein stabilization positive regulation of ubiquitin-protein transferase activity regulation of pathway-restricted SMAD protein phosphorylation positive regulation of cell growth involved in cardiac muscle cell development negative regulation of ERK1 and ERK2 cascade positive regulation of canonical Wnt signaling pathway regulation of protein localization to nucleus regulation of signal transduction by p53 class mediator negative regulation of cell motility

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