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Immunogen sequence: PKEMTKWNSN DFIDAFASPV EAEGTPEPGA EAAKGIEDGA QAPRDSEGLD GAGELGAEAC AVHALFLILH SGNILDSGP
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 81%.
Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Drosophila retinal degeneration B homolog; FLJ44997; Membrane-associated phosphatidylinositol transfer protein 1; NIR-2; phosphatidylinositol transfer protein, membrane associated 1; Phosphatidylinositol transfer protein, membrane-associated 1; PITPnm 1; PYK2 N-terminal domain-interacting receptor 2; retinal degeneration B alpha 1
Gene Aliases: DRES9; NIR2; PITPNM; PITPNM1; Rd9; RDGB; RDGB1; RDGBA; RDGBA1
UniProt ID: (Human) O00562
Entrez Gene ID: (Human) 9600
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