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MA5-17158 targets PRKACG in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17158 immunogen is purified recombinant fragment of human PRKACG expressed in E. Coli.
MA5-17158 detects PRKACG which has a predicted molecular weight of approximately 40.4kDa.
PRKACG (PRKAC gamma) is a third isoform of the catalytic subunit of cAMP-dependent protein kinase. It was isolated from a human testis cDNA library and was clearly derived from a gene distinct from C-alpha and C-beta and showed tissue-specific expression. Whereas at the amino acid level C-alpha and C-beta showed 93% homology, C-gamma showed only about 80% homology to both C-alpha and C-beta. The PRKACG gene is intronless, contains remnants of a poly(A) tail, is flanked by direct repeats, and is co-linear with the PRKACA gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gamma; protein kinase, cAMP-dependent, catalytic, gamma; protein kinase, cAMP-dependent, gamma catalytic subunit; serine(threonine) protein kinase
Gene Aliases: BDPLT19; KAPG; PKACg; PRKACG
UniProt ID: (Human) P22612
Entrez Gene ID: (Human) 5568
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