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Product Details
16792-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLCD3 Fusion Protein Ag10249 (441-789 aa encoded by BC072384)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AMARHLCTI LGDMLVTQAL DSPNPEELPS PEQLKGRVLV KGKKLPAARS EDGRALSDRE EEEEDDEEEE EEVEAAAQRR LAKQISPELS ALAVYCHATR LRTLHPAPNA PQPCQVSSLS ERKAKKLIRE AGNSFVRHNA RQLTRVYPLG LRMNSANYSP QEMWNSGCQL VALNFQTPGY EMDLNAGRFL VNGQCGYVLK PACLRQPDST FDPEYPGPPR TTLSIQVLTA QQLPKLNAEK PHSIVDPLVR IEIHGVPADC ARQETDYVLN NGFNPRWGQT LQFQLRAPEL ALVRFVVEDY DATSPNDFVG QFTLPLSSLK QGYRHIHLLS KDGASLSPAT LFIQIRIQRS (441-789 aa encoded by BC072384)
Target Information
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; Phosphoinositide phospholipase C-delta-3; phospholipase C, delta 3; Phospholipase C-delta-3; PLC delta3; PLC-delta-3
Gene Aliases: KIAA1964; PLC-delta-3; PLCD3
UniProt ID: (Human) Q8N3E9
Entrez Gene ID: (Human) 113026
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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