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Positive test controls include: NIH/3T3, SH-SY5Y, U-251MG, Mouse liver, Mouse brain, Mouse pancreas, Mouse eye, Rat liver.
Immunogen sequence: MLAVRKARRK LRMGTICSPN PSGTKTSSEV CNADWMASLP PHLHNLPLSN LAIPGSHDSF SYWVDEKSPV GPDQTQAIKR LARISLVKKL MKKWSVTQNL TFREQLEAGI RYFDLRVSSK PGDADQEIYF IHGLFGIKVW DGLMEIDSFL TQHPQEIIFL DFNHFYAMDE THHKCLVLRI QEAFGNKLCP ACSVESLTLR TLWEKNCQVL IFYHCPFYKQ YPFLWPGKKI PAPWANTTSV RKLILFLETT LSERASRGSF HVSQAILTPR VKTIARGLVG GLKNTLVHSN RWNSHGPSLL SQERS
PLC-XD2 (PI-PLC X domain-containing protein 2) is a 305 amino acid protein that contains a domain that is present in many PLC isozymes, the PI-PLC X (X-box)domain. Both the X-box domain and the Y-box domain are important for catalytic activity in PLC proteins. X-box domains are conserved from prokaryotes to mammals. The gene encoding PLC-XD2 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. There are two isoforms of PLC-XD2 that are produced as a result of alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: phosphatidylinositol-specific phospholipase C, X domain containing 2; Phospholipase C X-domain containing protein 2; PI-PLC X domain-containing protein 2; PLCXD-2
Gene Aliases: AW494639; EG433022; Plcxd2; RGD1563504
UniProt ID: (Mouse) B2RXA1
Entrez Gene ID: (Human) 257068, (Mouse) 433022, (Rat) 363781
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