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Immunogen sequence: SSLKRDMEKV ERQAVPQANH TESCHECGRV GPGHTRDCPH RGHDDIVNFE RQEQEGEQYR SQRDPLEGKR DRSKARSPYS PAEEDALFMD LPTGP
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 75%.
PLEKHA7 is required for zonula adherens biogenesis and maintenance. Acts via its interaction with KIAA1543/Nezha, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686M22243; PH domain-containing family A member 7; PH domain-containing family A member 7 antibody; pleckstrin homology domain containing A7 antibody; pleckstrin homology domain containing, family A member 2; pleckstrin homology domain containing, family A member 7; Pleckstrin homology domain-containing family A member 7
Gene Aliases: PLEKHA7
UniProt ID: (Human) Q6IQ23
Entrez Gene ID: (Human) 144100
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