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Immunogen sequence: VYGNIVIQKK KYNKQHIIPL ENVTIDSIKD EGDLRNGWLI KTPTKSFAVY AATATEKSEW MNHINKCVTD LLSKSGKTPS N
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
PLEKHF2 may play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EAPF; Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains; PH and FYVE domain-containing protein 2; PH domain-containing family F member 2; Phafin-2; Phafin2; pleckstrin homology domain containing, family F (with FYVE domain) member 2; Pleckstrin homology domain-containing family F member 2; Zinc finger FYVE domain-containing protein 18
Gene Aliases: EAPF; PHAFIN2; PLEKHF2; ZFYVE18
UniProt ID: (Human) Q9H8W4
Entrez Gene ID: (Human) 79666
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