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PLXNB2 Antibody (PA5-112655) in WB
Western Blot analysis of PLXNB2 in multiple sample types using a PLXNB2 polyclonal antibody (Product # PA5-112655) at a dilution of 1:1000. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000. Sample types that were tested include: A549 whole cell lysate, 293 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate .
Product Details
PA5-112655
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human Inhibitor of nuclear factor kappa-B kinase-interacting protein (1458-1673AA)
Conjugate
Form
Liquid
Concentration
0.68 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_2867390
Target Information
Plexin-B2 is a member of the Semaphorin receptor family. The semaphorin family consists of membrane and secreted proteins involved in attraction and repulsion of neuronal guidance cues. Plexin-B1 is a transmembrane protein that can be cleaved converting the single chain precursor into a heterodimeric receptor. It has been shown to bind Sema4D/CD100 and is involved in axon development in mouse embryos. Sema4D also plays a role in the immune system interacting with CD72. Plexin-B2's possible role in the immune system has not been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MM1; MM1KIAA0315dJ402G11.3; Plexin-B2
Gene Aliases: dJ402G11.3; KIAA0315; MM1; Nbla00445; PLEXB2; PLXNB2
UniProt ID: (Human) O15031
Entrez Gene ID: (Human) 23654
neural tube closure
regulation of protein phosphorylation
homophilic cell adhesion via plasma membrane adhesion molecules
negative regulation of cell adhesion
neuroblast proliferation
brain development
regulation of cell shape
positive regulation of neuron projection development
regulation of cell migration
regulation of GTPase activity
positive regulation of axonogenesis
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
regulation of neuron migration
Performance Guarantee
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