Product References
High expression of peroxisomal D-bifunctional protein in cytosol regulates apoptosis and energy metabolism of hepatocellular carcinoma cells via PI3K/AKT pathway.
American journal of cancer research
Zhang N,Wang YQ,Sun C,Shi Y,Hou LG,Yao M,Hu M,Wang XM,Ma PP,Li WJ,Jiang LL
PA1-650 was used in Western Blot to find that DBP expression was upregulated in HCC tumor tissues, and higher DBP expression was positively correlated with tumor size and TNM stage.
Mon Jun 12 00:00:00 UTC 2023
CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.
Cells
Braccia C,Christopher JA,Crook OM,Breckels LM,Queiroz RML,Liessi N,Tomati V,Capurro V,Bandiera T,Baldassari S,Pedemonte N,Lilley KS,Armirotti A
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Immunocytochemistry
Thu Jun 16 00:00:00 UTC 2022
CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.
Cells
Braccia C,Christopher JA,Crook OM,Breckels LM,Queiroz RML,Liessi N,Tomati V,Capurro V,Bandiera T,Baldassari S,Pedemonte N,Lilley KS,Armirotti A
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Immunocytochemistry
Thu Jun 16 00:00:00 UTC 2022
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering.
The Journal of cell biology
Zappa F,Muniozguren NL,Wilson MZ,Costello MS,Ponce-Rojas JC,Acosta-Alvear D
PA1-650 was used in Immunocytochemistry-immunofluorescence to support a model in which PKR clustering may limit encounters between PKR and eIF2α to buffer downstream signaling and prevent the ISR from misfiring.
Mon Jul 04 00:00:00 UTC 2022
Genotype-phenotype correlations and disease mechanisms in PEX13-related Zellweger spectrum disorders.
Orphanet journal of rare diseases
Borgia P,Baldassari S,Pedemonte N,Alkhunaizi E,D'Onofrio G,Tortora D,Calì E,Scudieri P,Balagura G,Musante I,Diana MC,Pedemonte M,Vari MS,Iacomino M,Riva A,Chimenz R,Mangano GD,Mohammadi MH,Toosi MB,Ashrafzadeh F,Imannezhad S,Karimiani EG,Accogli A,Schiaffino MC,Maghnie M,Soler MA,Echiverri K,Abrams CK,Striano P,Fortuna S,Maroofian R,Houlden H,Zara F,Fiorillo C,Salpietro V
PA1-650 was used in Immunohistochemistry to expand the phenotypic and mutational spectrum of PEX13-related ZSDs and also highlight a variety of disease mechanisms contributing to PEX13-related clinical phenotypes, including the emerging contribution of secondary mitochondrial dysfunction to the pathophysiology of ZSDs.
Tue Jul 19 00:00:00 UTC 2022
Changes in NAD and Lipid Metabolism Drive Acidosis-Induced Acute Kidney Injury.
Journal of the American Society of Nephrology : JASN
Bugarski M,Ghazi S,Polesel M,Martins JR,Hall AM
PA1-650 was used immunohistochemistry (paraffin) investigate the extent to which Metabolic acidosis (MA) causes Acute Kidney Injury, and thus whether treating MA would be beneficial.
Mon Feb 01 00:00:00 UTC 2021
PI5P4Ks drive metabolic homeostasis through peroxisome-mitochondria interplay.
Developmental cell
Ravi A,Palamiuc L,Loughran RM,Triscott J,Arora GK,Kumar A,Tieu V,Pauli C,Reist M,Lew RJ,Houlihan SL,Fellmann C,Metallo C,Rubin MA,Emerling BM
PA1-650 was used in Immunocytochemistry-immunoflourescence to reveal an unexplored role for PI5P4Ks in preserving metabolic homeostasis, which is necessary for tumorigenesis.
Mon Jun 07 00:00:00 UTC 2021
The molecular and metabolic program by which white adipocytes adapt to cool physiologic temperatures.
PLoS biology
Mori H,Dugan CE,Nishii A,Benchamana A,Li Z,Cadenhead TS,Das AK,Evans CR,Overmyer KA,Romanelli SM,Peterson SK,Bagchi DP,Corsa CA,Hardij J,Learman BS,El Azzouny M,Coon JJ,Inoki K,MacDougald OA
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Western Blot
Sat May 01 00:00:00 UTC 2021
Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect.
Frontiers in cell and developmental biology
Klouwer FCC,Falkenberg KD,Ofman R,Koster J,van Gent D,Ferdinandusse S,Wanders RJA,Waterham HR
PA1-650 was used in Western Blotting to study whether autophagy inhibitors chloroquine, hydroxychloroquine and 3-methyladenine can improve peroxisomal functions in different cell types with the PEX1-G843D mutation.
Sat Nov 11 00:00:00 UTC 2023
Autophagy Inhibitors Do Not Restore Peroxisomal Functions in Cells With the Most Common Peroxisome Biogenesis Defect.
Frontiers in cell and developmental biology
Klouwer FCC,Falkenberg KD,Ofman R,Koster J,van Gent D,Ferdinandusse S,Wanders RJA,Waterham HR
PA1-650 was used in Western Blotting to study whether autophagy inhibitors chloroquine, hydroxychloroquine and 3-methyladenine can improve peroxisomal functions in different cell types with the PEX1-G843D mutation.
Sat Nov 11 00:00:00 UTC 2023
The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis.
Journal of inherited metabolic disease
Ranea-Robles P,Chen H,Stauffer B,Yu C,Bhattacharya D,Friedman SL,Puchowicz M,Houten SM
PA1-650 was used in Western Blot to provide data on the role of the peroxisomal transporter ABCD3 in hepatic lipid homeostasis and DCA metabolism, and the consequences of peroxisomal dysfunction for the liver.
Mon Nov 01 00:00:00 UTC 2021
Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.
Kidney360
Ranea-Robles P,Portman K,Bender A,Lee K,He JC,Mulholland DJ,Argmann C,Houten SM
PA1-650 was used in Western Blot to assess the role of androgens in the kidney phenotype of Ehhadh KO mice.
Wed Sep 01 00:00:00 UTC 2021
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting.
Journal of cell science
Evans AJ,Daly JL,Anuar ANK,Simonetti B,Cullen PJ
PA1-650 was used in Immunocytochemistry-immunoflourescence to show the role for retromer in ESCPE-1-mediated CI-MPR retrograde sorting, and establish a methodology for acute retromer and ESCPE-1 inactivation that will aid the time-resolved dissection of their function role in endosomal cargo sorting.
Mon Aug 03 00:00:00 UTC 2020
Alternative Splicing and Cleavage of GLUT8.
Molecular and cellular biology
Alexander CM,Martin JA,Oxman E,Kasza I,Senn KA,Dvinge H
PA1-650 was used in Immunohistochemistry to reveal a lysosome-dependent reaction that cleaves the GLUT8 protein and releases the carboxy-terminal peptide to a separate vesicle population.
Mon Dec 21 00:00:00 UTC 2020
Accelerating multicolor spectroscopic single-molecule localization microscopy using deep learning.
Biomedical optics express
Kumar Gaire S,Zhang Y,Li H,Yu R,Zhang HF,Ying L
PA1-650 was used in Immunocytochemistry-immunoflourescence to generate multicolor super-resolution images within a much shorter time, without any changes in the existing sSMLM hardware system.
Fri May 01 00:00:00 UTC 2020
Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors.
Hepatology communications
Preidis GA,Soni KG,Suh JH,Halder T,Kim KH,Choi JM,Li F,Devaraj S,Conner ME,Coarfa C,Jung SY,Moore DD
PA1-650 was used in Western Blotting to show that malnutrition impairs growth and liver synthetic function more severely in male mice than in female mice.
Tue Dec 01 00:00:00 UTC 2020
Coagulopathy in Malnourished Mice Is Sexually Dimorphic and Regulated by Nutrient-Sensing Nuclear Receptors.
Hepatology communications
Preidis GA,Soni KG,Suh JH,Halder T,Kim KH,Choi JM,Li F,Devaraj S,Conner ME,Coarfa C,Jung SY,Moore DD
PA1-650 was used in Western Blotting to show that malnutrition impairs growth and liver synthetic function more severely in male mice than in female mice.
Tue Dec 01 00:00:00 UTC 2020
Feature-rich covalent stains for super-resolution and cleared tissue fluorescence microscopy.
Science advances
Mao C,Lee MY,Jhan JR,Halpern AR,Woodworth MA,Glaser AK,Chozinski TJ,Shin L,Pippin JW,Shankland SJ,Liu JTC,Vaughan JC
PA1-650 was used in Immunocytochemistry to report the use of conventional, commercially available fluorescent dyes for rapid and intense covalent labeling of proteins and carbohydrates in super-resolution (expansion) microscopy and cleared tissue microscopy.
Fri May 01 00:00:00 UTC 2020
Symmetrically dispersed spectroscopic single-molecule localization microscopy.
Light, science & applications
Song KH,Zhang Y,Brenner B,Sun C,Zhang HF
PA1-650 was used in SDsSMLM imaging to demonstrate multicolour imaging of fixed cells and three-dimensional single-particle tracking using SDsSMLM.
Mon Sep 11 00:00:00 UTC 2023
Ceapins block the unfolded protein response sensor ATF6α by inducing a neomorphic inter-organelle tether.
eLife
Torres SE,Gallagher CM,Plate L,Gupta M,Liem CR,Guo X,Tian R,Stroud RM,Kampmann M,Weissman JS,Walter P
PA1-650 was used in Western Blotting to reveal that Ceapins function by chemical-induced misdirection.
Fri May 31 00:00:00 UTC 2019
A Phosphatidylinositol 3-Kinase Effector Alters Phagosomal Maturation to Promote Intracellular Growth of Francisella.
Cell host & microbe
Ledvina HE,Kelly KA,Eshraghi A,Plemel RL,Peterson SB,Lee B,Steele S,Adler M,Kawula TH,Merz AJ,Skerrett SJ,Celli J,Mougous JD
PA1-650 was used in Immunocytochemistry to suggest that Francisella, and likely other intracellular bacteria, override the finely tuned dynamics of phagosomal PI(3)P in order to promote intracellular survival and pathogenesis.
Wed Aug 08 00:00:00 UTC 2018
Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.
The Journal of biological chemistry
Young PA,Senkal CE,Suchanek AL,Grevengoed TJ,Lin DD,Zhao L,Crunk AE,Klett EL,Füllekrug J,Obeid LM,Coleman RA
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Immunoprecipitation
Fri Oct 26 00:00:00 UTC 2018
Long-chain acyl-CoA synthetase 1 interacts with key proteins that activate and direct fatty acids into niche hepatic pathways.
The Journal of biological chemistry
Young PA,Senkal CE,Suchanek AL,Grevengoed TJ,Lin DD,Zhao L,Crunk AE,Klett EL,Füllekrug J,Obeid LM,Coleman RA
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Immunoprecipitation
Fri Oct 26 00:00:00 UTC 2018
UBL3 modification influences protein sorting to small extracellular vesicles.
Nature communications
Ageta H,Ageta-Ishihara N,Hitachi K,Karayel O,Onouchi T,Yamaguchi H,Kahyo T,Hatanaka K,Ikegami K,Yoshioka Y,Nakamura K,Kosaka N,Nakatani M,Uezumi A,Ide T,Tsutsumi Y,Sugimura H,Kinoshita M,Ochiya T,Mann M,Setou M,Tsuchida K
PA1-650 was used in Immunocytochemistry to study the molecular mechanism by which proteins are sorted to small extracellular vesicles.
Wed Sep 26 00:00:00 UTC 2018
Peroxisomal protein PEX13 functions in selective autophagy.
EMBO reports
Lee MY,Sumpter R,Zou Z,Sirasanagandla S,Wei Y,Mishra P,Rosewich H,Crane DI,Levine B
PA1-650 was used in immunocytochemistry to study the role of PEX13 in autophagy
Sun Jan 01 00:00:00 UTC 2017
Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism.
PLoS pathogens
Sychev ZE,Hu A,DiMaio TA,Gitter A,Camp ND,Noble WS,Wolf-Yadlin A,Lagunoff M
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism.
PLoS pathogens
Sychev ZE,Hu A,DiMaio TA,Gitter A,Camp ND,Noble WS,Wolf-Yadlin A,Lagunoff M
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism.
PLoS pathogens
Sychev ZE,Hu A,DiMaio TA,Gitter A,Camp ND,Noble WS,Wolf-Yadlin A,Lagunoff M
Published figure using PMP70 polyclonal antibody (Product # PA1-650) in Flow Cytometry
Wed Mar 01 00:00:00 UTC 2017
Flow Cytometric Analysis of the Expression Pattern of Peroxisomal Proteins, Abcd1, Abcd2, and Abcd3 in BV-2 Murine Microglial Cells.
Methods in molecular biology (Clifton, N.J.)
Debbabi M,Nury T,Helali I,Karym EM,Geillon F,Gondcaille C,Trompier D,Najid A,Terreau S,Bezine M,Zarrouk A,Vejux A,Andreoletti P,Cherkaoui-Malki M,Savary S,Lizard G
PA1-650 was used in Flow cytometry/Cell sorting to evaluate the expression pattern of various peroxisomal transporters (Abcd1, Abcd2, Abcd3) contributing to peroxisomal β-oxidation in BV-2 cells.
Thu May 18 00:00:00 UTC 2017
LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.
eLife
Lin JP,Mironova YA,Shrager P,Giger RJ
PA1-650 was used in Immunocytochemistry to reveal a novel role for low-density lipoprotein receptor-related protein-1 in peroxisome biogenesis, lipid homeostasis, and oligodendrocyte progenitor cell differentiation during white matter development and repair.
Mon Dec 18 00:00:00 UTC 2017
Peroxisomal localization of the proopiomelanocortin-derived peptides beta-lipotropin and beta-endorphin.
Endocrinology
Höftberger R,Kunze M,Voigtländer T,Unterberger U,Regelsberger G,Bauer J,Aboul-Enein F,Garzuly F,Forss-Petter S,Bernheimer H,Berger J,Budka H
PA1-650 was used in western blot to study the sub-cellular localisation of beta-lipotropin and beta-endorphin.
Fri Oct 01 00:00:00 UTC 2010
Gene expression analysis in rats treated with experimental acetyl-coenzyme A carboxylase inhibitors suggests interactions with the peroxisome proliferator-activated receptor alpha pathway.
The Journal of pharmacology and experimental therapeutics
Waring JF,Yang Y,Healan-Greenberg CH,Adler AL,Dickinson R,McNally T,Wang X,Weitzberg M,Xu X,Lisowski A,Warder SE,Gu YG,Zinker BA,Blomme EA,Camp HS
PA1-650 was used in immunohistochemistry to investigate the pharmacological functions of small-molecule inhibitors of ACC3 by means of gene expression analysis
Fri Feb 01 00:00:00 UTC 2008
Peroxisome proliferator-activated receptor-alpha regulates postischemic liver injury.
American journal of physiology. Gastrointestinal and liver physiology
Okaya T,Lentsch AB
PA1-650 was used in western blot to study the regulation of postischemic liver injury by PPAP alpha
Thu Apr 01 00:00:00 UTC 2004
Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes.
The Journal of biological chemistry
Su X,Mancuso DJ,Bickel PE,Jenkins CM,Gross RW
PA1-650 was used in immunocytochemistry and western blot to study the effect of calcium-independent phospholipases A2 beta or gamma on 3T3-L1 preadipocyte differentiation
Fri May 21 00:00:00 UTC 2004
Expression of fatty acid binding proteins inhibits lipid accumulation and alters toxicity in L cell fibroblasts.
American journal of physiology. Cell physiology
Atshaves BP,Storey SM,Petrescu A,Greenberg CC,Lyuksyutova OI,Smith R,Schroeder F
PA1-650 was used in western blot to investigate the role of expression of fatty acid binding proteins on lipid accumulation in L cell fibroblasts
Sun Sep 01 00:00:00 UTC 2002
