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OriGene

PNMT Monoclonal Antibody (OTI1D2), TrueMAB™

View all (50) PNMT antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (7)

Application

PNMT Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 7

PNMT Antibody (TA502822) in ICC/IF

Anti-PNMT mouse monoclonal antibody (TA502822) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PNMT(RC206586).

PNMT Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

TA502822

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

1:150

Immunocytochemistry (ICC/IF)

1:100

Product Specifications

Species Reactivity

Dog, Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

OTI1D2

Immunogen

Full length human recombinant protein of human PNMT produced in HEK293T cell.

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Noradrenaline N-methyltransferase; phenylethanolamine N-methylase; Phenylethanolamine N-methyltransferase; PNMTase

Gene Aliases: PENT; PNMT; PNMTase

UniProt ID: (Human) P11086, (Mouse) P40935, (Rat) P10937

Entrez Gene ID: (Human) 5409, (Dog) 491023, (Mouse) 18948, (Rat) 24661

Function(s)

phenylethanolamine N-methyltransferase activity methyltransferase activity transferase activity S-adenosylmethionine-dependent methyltransferase activity methyltransferase

Process(es)

methylation epinephrine biosynthetic process catecholamine biosynthetic process norepinephrine metabolic process response to hypoxia response to cold response to water deprivation response to activity adrenal gland development response to corticosteroid response to insulin social behavior response to isolation stress response to immobilization stress response to peptide hormone response to ethanol response to ether S-adenosylhomocysteine metabolic process S-adenosylmethionine metabolic process sensory perception of taste cellular response to growth factor stimulus cellular response to peptide hormone stimulus cellular response to dexamethasone stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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