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Application
FIGURE: 1 / 1
POC1A Antibody (PA5-110190) in WB
Western blot analysis of POC1A in extracts of various cell lines. Samples were incubated with POC1A Polyclonal antibody (Product # PA5-110190) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-110190
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 138-407 of human POC1A (NP_056241.3).
Conjugate
Unconjugated
Form
Liquid
Concentration
1.4 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855601
Product Specific Information
Immunogen sequence: LFSLSQHINW VRCAKFSPDG RLIVSASDDK TVKLWDKSSR ECVHSYCEHG GFVTYVDFHP SGTCIAAAGM DNTVKVWDVR THRLLQHYQL HSAAVNGLSF HPSGNYLITA SSDSTLKILD LMEGRLLYTL HGHQGPATTV AFSRTGEYFA SGGSDEQVMV WKSNFDIVDH GEVTKVPRPP ATLASSMGNL PEVDFPVPPG RGRSVESVQS QPQEPVSVPQ TLTSTLEHIV GQLDVLTQTV SILEQRLTLT EDKLKQCLEN QQLIMQRATP
Target Information
POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutations in this gene result in short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT) syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Pix2; POC1 centriolar protein homolog A; Proteome of centriole protein 1A; WD repeat domain 51A; WD repeat-containing protein 51A
Gene Aliases: 2510040D07Rik; PIX2; POC1A; RGD1565004; SOFT; WDR51A
UniProt ID: (Human) Q8NBT0, (Mouse) Q8JZX3
Entrez Gene ID: (Human) 25886, (Mouse) 70235, (Rat) 501048
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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