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Abnova
POU6F2 Monoclonal Antibody (1D3)
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Product Details
H00011281-M05
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
1D3
Immunogen
POU6F2 (NP_009183, 2 a.a. approximately 87 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: IAGQVSKPLL SVRSEMNAEL RGEDKAATSD SELNEPLLAP VESNDSEDTP SKLFGARGNP ALSDPGTPDQ HQASQTHPPF PVGPQP
Target Information
This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: POU domain class 6 transcription factor 2; POU domain, class 6, transcription factor 2; Retina-derived POU domain factor 1; retina-derived POU-domain factor-1; RPF-1; Wilms tumor suppressor locus
Gene Aliases: POU6F2; RPF-1; RPF1; WT5; WTSL
UniProt ID: (Human) P78424
Entrez Gene ID: (Human) 11281
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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