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Product Details
H00008611-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPAP2A (NP_003702.2, 1 a.a. approximately 284 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFDKTRLPYV ALDVLCVLLA GLPFAILTSR HTPFQRGVFC NDESIKYPYK EDTIPYALLG GIIIPFSIIV IILGETLSVY CNLLHSNSFI RNNYIATIYK AIGTFLFGAA ASQSLTDIAK YSIGRLRPHF LDVCDPDWSK INCSDGYIEY YICRGNAERV KEGRLSFYSG HSSFSMYCML FVALYLQARM KGDWARLLRP TLQFGLVAVS IYVGLSRVSD YKHHWSDVLT GLIQGALVAI LVAVYVSDFF KERTSFKERK EEDSHTTLHE TPTTGNHYPS NHQP
Target Information
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Lipid phosphate phosphohydrolase 1; lipid phosphate phosphohydrolase 1a; PAP-2a; PAP2-alpha; PAP2alpha2; PAPalpha1; Phosphatidate phosphohydrolase type 2a; Phosphatidic acid phosphatase 2a; phosphatidic acid phosphatase type 2A; phosphatidic acid phosphohydrolase type 2a; Phospholipid phosphatase 1; type-2 phosphatidic acid phosphatase alpha
Gene Aliases: LLP1a; LPP1; PAP-2a; PAP2; PLPP1; PPAP2A
UniProt ID: (Human) O14494
Entrez Gene ID: (Human) 8611
protein dephosphorylation
lipid metabolic process
phospholipid metabolic process
protein kinase C-activating G-protein coupled receptor signaling pathway
negative regulation of cell proliferation
germ cell migration
regulation of lipid metabolic process
sphingolipid biosynthetic process
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
phospholipid dephosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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