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Invitrogen
PPM1G Monoclonal Antibody (528322)
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Application
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PPM1G Antibody (MA5-24230) in WB
Western blot analysis of PPM1G in HUVEC human umbilical vein endothelial cells and HeLa human cervical epithelial carcinoma cell line. Samples were incubated in PPM1G monoclonal antibody (Product # MA5-24230) using a dilution of 0.25 µg/mL followed by a HRP-conjugated Anti-Mouse IgG secondary antibody. A specific band was detected for PP2Cγ/PPM1G at approximately 75 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
MA5-24230
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
528322
Immunogen
E. coli-derived recombinant human PP2C gamma Met1-Asp546
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2610352
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PP2C, gamma; PP2C-gamma; Protein phosphatase 1C; Protein phosphatase 1G; protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform; protein phosphatase 2, catalytic subunit, gamma isoform; protein phosphatase 2C gamma isoform; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; protein phosphatase, Mg2+/Mn2+ dependent, 1G
Gene Aliases: PP2CG; PP2CGAMMA; PPM1C; PPM1G; PPP2CG
UniProt ID: (Human) O15355
Entrez Gene ID: (Human) 5496
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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