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PRKCBP1 Antibody (A302-089A) in WB
Detection of human PRKCBP1 by western blot and immunoprecipitation. Samples: Whole cell lysate (5, 15 and 50 µg for WB; 1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PRKCBP1 antibody A302-089A used for WB at 0.1 µg/ml (A) and 1 µg/ml (B) and used for IP at 3 µg/mg lysate. PRKCBP1 was also immunoprecipitated by rabbit anti-PRKCBP1 antibody A302-090A, which recognizes a downstream epitope. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds ... View More
Product Details
A302-089A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 775 and 825 of Human protein kinase C binding protein 1 (zinc finger, MYND-type containing 8).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTCL tumor antigen se14-3; CTCL-associated antigen se14-3; Cutaneous T-cell lymphoma-associated antigen se14-3; MYND-type zinc finger-containing chromatin reader ZMYND8; predicted protein of HQ2893; Protein kinase C-binding protein 1; Rack7; Transcription coregulator ZMYND8; Zinc finger MYND domain-containing protein 8; zinc finger, MYND-type containing 8
Gene Aliases: KIAA1125; PRKCBP1; PRO2893; RACK7; ZMYND8
UniProt ID: (Human) Q9ULU4
Entrez Gene ID: (Human) 23613
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
positive regulation of filopodium assembly
positive regulation of dendritic spine development
modulation of excitatory postsynaptic potential
regulation of postsynaptic density protein 95 clustering
positive regulation of dendritic spine maintenance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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