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Application
FIGURE: 1 / 1
PRPF40A Antibody (PA5-75938) in WB
Western blot analysis of PRPF40A in Lane 1: HeLa whole cell lysate (40 µg), Lane 2: the Brain tissue lysate of rat (30 µg), Lane 3: the Brain tissue lysate of mouse (30 µg). Samples were incubated with PRPF40A polyclonal antibody (Product # PA5-75938) at a dilution of 1:500.
Product Details
PA5-75938
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 466-511 of Human PRPF40A.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719666
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
FNBP3, Formin-binding protein 3, is a 957 amino acid protein encoded by the human gene PRPF40A. FNBP3 belongs to the PRPF40 family and contains five FF domains and two WW domains. Nuclear proteins harboring both WW and FF protein interaction modules bind to splicing factors as well as RNA polymerase II and may serve to link transcription with splicing. Through the WW domains, FNBP3 will bind to the Formin proline-rich regions. Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 binds to WASL/N-WASP (Neuronal Wiskott-Aldrich syndrome protein) complex and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. FNBP3 is widely expressed in most tissues and is localized to the nuclear speckles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Fas ligand-associated factor 1; Fas-ligand associated factor 1; FBP-11; FLJ20585; formin binding protein 11; formin binding protein 3; Formin-binding protein 11; Formin-binding protein 3; HIP-10; Huntingtin yeast partner A; Huntingtin-interacting protein 10; Huntingtin-interacting protein A; NY-REN-6 antigen; pre-mRNA processing factor 40 homolog A; Pre-mRNA-processing factor 40 homolog A; PRP40 pre-mRNA processing factor 40 homolog A; Renal carcinoma antigen NY-REN-6
Gene Aliases: 2810012K09Rik; FBP-11; FBP11; FLAF1; Fnbp11; FNBP3; HIP-10; HIP10; HSPC225; HYPA; NY-REN-6; Prp40; PRPF40A
UniProt ID: (Human) O75400, (Mouse) Q9R1C7
Entrez Gene ID: (Human) 55660, (Rat) 295607, (Mouse) 56194
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