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产品信息
19515-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide
偶联物
Unconjugated
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
PRSS27, also known as Marapsin, is a gene located on chromosome 16p13.3 that encodes a serine protease enzyme. This protein is part of the trypsin-like serine protease family, which is characterized by a catalytic triad essential for proteolytic activity. PRSS27 is primarily expressed in the epidermis and other epithelial tissues, such as the salivary glands and pancreas. It plays a role in various physiological processes, including digestion, inflammation, and immune response regulation. In the skin, PRSS27 is involved in keratinocyte differentiation and the maintenance of skin barrier function. Dysregulation or altered expression of PRSS27 has been associated with inflammatory skin conditions, such as psoriasis, where it may influence the inflammatory cascade and contribute to disease pathogenesis. Research into PRSS27 continues to explore its potential role in epithelial homeostasis and as a therapeutic target for skin-related and other inflammatory disorders.
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生物信息学
蛋白别名: CAP-2; channel-activating protease 2; channel-activating protease 2-like protein; EC 3.4.21; EC 3.4.21.4; EC 3.4.21.43; Marapsin; MPNMarapsin; Pancreasin; Serine protease 27
基因别名: CAPH2; marapsin; MPN; PRSS27; UNQ1884/PRO4327
UniProt ID: (Human) Q9BQR3, (Mouse) Q8BJR6
Entrez Gene ID: (Human) 83886, (Mouse) 213171
