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Product Details
11809-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSG1 Fusion Protein Ag2468 (36-350 aa encoded by BC022338)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VTIEAEPTK VSEGKDVLLL VHNLPQNLTG YIWYKGQMRD LYHYITSYVV DGEIIIYGPA YSGRETAYSN ASLLIQNVTR EDAGSYTLHI IKGDDGTRGV TGRFTFTLHL ETPKPSISSS NLNPRETMEA VSLTCDPETP DASYLWWMNG QSLPMTHSLK LSETNRTLFL LGVTKYTAGP YECEIRNPVS ASRSDPVTLN LLPKLPKPYI TINNLNPREN KDVLNFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYQCEIRD RYGGIRSDPV TLNVLYGPDL PRIYPSFTYY RSGEVL (36-350 aa encoded by BC022338)
Target Information
Human pregnancy-specific glycoproteins (PSG), are a group of closely related secreted glycoproteins which are highly expressed in placental syncytiotrophoblast cells of fetal origin. PSG are commonly expressed in tumors of trophoblast origin (hydatidiform mole, choriocarcinoma). They represent the most abundant fetal protein in the maternal blood at term. The eleven human PSG genes (PSG1-PSG11) form together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes. CD9 was shown to represent the monocyte receptor for murine PSG17. PSG are thought to modulate the maternal immune system during pregnancy thus protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD66 antigen-like family member F; CD66f; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; FLJ90598; FLJ90654; pregnancy-specific B-1 glycoprotein; Pregnancy-specific beta-1 glycoprotein C/D; Pregnancy-specific beta-1-glycoprotein 1; PS-beta-C/D; PS-beta-G-1; PSG 1; PSG IIA-d; PSG-1d; PSG95; PSGIIA-a; PSGIIA-b; PSGIIA-c; SP 1
Gene Aliases: B1G1; CD66f; DHFRP2; FL-NCA-1/2; PBG1; PS-beta-C/D; PS-beta-G-1; PSBG-1; PSBG1; PSG1; PSG95; PSGGA; PSGIIA; SP1
UniProt ID: (Human) P11464
Entrez Gene ID: (Human) 5669
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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