Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGPLSAPPCT EHIKWKGLLL TASLLNFWNL PTTAQVTIEA QPPKVSEGKD VLLLVHNLPQ NLTGYIWYKG QIRDLYHYIT SYVVDGQIII YGPAYSGRET AYSNASLLIQ NVTREDAGSY TLHIIKRGDG TRGVTGYFTF TLYLETPKPS ISSSNLNPRE AMETVILTCD PETPDTSYQW WMNGQSLPMT HRFQLSETNR TLFLFGVTKY TAGPYECEIR NSGSASRSDP VTLNLLHGPD LPRIHPSYTN YRSGDNLYLS CFANSNPPAQ YSWTINGKFQ QSGQNLFIPQ ITTKHSGLYV CSVRNSATGE ESSTSLTVKV SASTRIGLLP LLNPT
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: carcinoembryonic antigen SG8; Pregnancy-specific beta-1 glycoprotein E; Pregnancy-specific beta-1-glycoprotein 2; pregnancy-specific beta-1-glycoprotein 7; pregnancy-specific beta-1-glycoprotein-2; pregnancy-specific glycoprotein 2; PS-beta-E; PS-beta-G-2; PSBG-2
Gene Aliases: CEA; PSBG2; PSG1; PSG2
UniProt ID: (Human) P11465
Entrez Gene ID: (Human) 5670
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