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Proteintech

PSMB2 Polyclonal Antibody

5 References

View all (13) PSMB2 antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Catalog # 15154-1-AP

Preis (EUR)

437,00

150 µL

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Datasheet

Protocols

Questions & Answers

Tech Support

Antibody Testing Data (8)

Application

PSMB2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

PSMB2 Antibody (15154-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells using 15154-1-AP (PSMB2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PSMB2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

15154-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PSMB2 Fusion Protein Ag7198 (1-201 aa encoded by BC000268)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEYLIGIQG PDYVLVASDR VAASNIVQMK DDHDKMFKMS EKILLLCVGE AGDTVQFAEY IQKNVQLYKM RNGYELSPTA AANFTRRNLA DCLRSRTPYH VNLLLAGYDE HEGPALYYMD YLAALAKAPF AAHGYGAFLT LSILDRYYTP TISRERAVEL LRKCLEELQK RFILNLPTFS VRIIDKNGIH DLDNISFPKQ GS (1-201 aa encoded by BC000268)

Target Information

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Inhibition of the Proteasome Regulator PA28 Aggravates Oxidized Protein Overload in the Diabetic Rat Brain.

Cellular and molecular neurobiology

Wu DG,Wang YN,Zhou Y,Gao H,Zhao B

Tue Aug 01 00:00:00 UTC 2023

Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats.

Metabolic brain disease

Gao H,Zhou Y,Jin PS,Wu DG,Wang YN,Zhao X,Zhao B

Wed Mar 01 00:00:00 UTC 2023

Selective Inhibition of the Immunoproteasome β5i Prevents PTEN Degradation and Attenuates Cardiac Hypertrophy.

Frontiers in pharmacology

Xie X,Wang HX,Li N,Deng YW,Bi HL,Zhang YL,Xia YL,Li HH

Mon Sep 28 00:00:00 UTC 2020

Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity.

Molecular cancer research : MCR

Shi CX,Zhu YX,Bruins LA,Bonolo de Campos C,Stewart W,Braggio E,Stewart AK

Thu Oct 01 00:00:00 UTC 2020

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.

Oncogene

Tan S,Li H,Zhang W,Shao Y,Liu Y,Guan H,Wu J,Kang Y,Zhao J,Yu Q,Gu Y,Ding K,Zhang M,Qian W,Zhu Y,Cai H,Chen C,Lobie PE,Zhao X,Sun J,Zhu T

Wed Aug 01 00:00:00 UTC 2018

NUDT21 negatively regulates PSMB2 and CXXC5 by alternative polyadenylation and contributes to hepatocellular carcinoma suppression.

Oncogene

Tan S,Li H,Zhang W,Shao Y,Liu Y,Guan H,Wu J,Kang Y,Zhao J,Yu Q,Gu Y,Ding K,Zhang M,Qian W,Zhu Y,Cai H,Chen C,Lobie PE,Zhao X,Sun J,Zhu T

Wed Aug 01 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: beta-4; Macropain subunit C7-I; multicatalytic endopeptidase complex subunit C7-1; Multicatalytic endopeptidase complex subunit C7-I; proteasome (prosome, macropain) subunit, beta type, 2; proteasome beta 2 subunit; Proteasome component C7-I; Proteasome subunit beta type-2; Proteasome subunit beta-4; proteasome subunit, beta type, 2; testicular tissue protein Li 152

Gene Aliases: HC7-I; PSMB2

UniProt ID: (Human) P49721

Entrez Gene ID: (Human) 5690

Function(s)

Process(es)

MAPK cascade protein polyubiquitination stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent regulation of cellular amino acid metabolic process response to organonitrogen compound response to organic cyclic compound viral process anaphase-promoting complex-dependent catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PSMB2 Polyclonal Antibody

PSMB2 Antibody (15154-1-AP) in ICC/IF

Product Details

15154-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Function(s)

Process(es)

Performance Guarantee

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