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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • PSMC6 Antibodies

            Bethyl Laboratories

            PSMC6 Polyclonal Antibody

            View all (17) PSMC6 antibodies
            Datasheet
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            Datasheet
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            Cite PSMC6 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            PSMC6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            PSMC6 Antibody (A303-825A-T) in IHC (P)

            Detection of human PSMC6 by immunohistochemistry. Samples: FFPE serial sections of human lung carcinoma. Antibody: Affinity purified rabbit anti-PSMC6 (Product # A303-824A) (Lot 1, left image) and (Product # A303-825A) (Lot 1, right image) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. Counterstain: hematoxylin (blue).
            View Product

            PSMC6 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            PSMC6 Antibody in Western Blot (WB)

            Product Details

            A303-825A-T

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000-1:10,000
            -

            Immunohistochemistry (IHC)

            1:500-1:2,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:500-1:2,000
            -

            Immunoprecipitation (IP)

            2-10 µg/mg lysate
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Region between residue 339 and 389 of Human Proteasome (prosome, macropain) Subunit, ATPase, 6.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            phosphate/tris citrate, pH 7-8

            Contains

            0.09% sodium azide

            Storage conditions

            4°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            The recommended shelf life for this product is 1 year from date of receipt.

            Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

            Based on 100% sequence identity, this antibody is predicted to react with Bovine

            Target Information

            PSMC6 (proteasome (prosome, macropain) 26S subunit, ATPase 6), also known as P44, p42, SUG2, S10B or CADP44, is a regulatory component of the 26S proteasome. More specifically, PSMC6 is one of the six ATPase subunits of the 19S regulator base. It contains a leucine zipper motif and an AAA (ATPase associated with diverse cellular activities) domain and belongs to the AAA ATPase family of chaperone-like ATPases.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: 26S protease regulatory subunit 10B; 26S protease regulatory subunit S10B; 26S proteasome AAA-ATPase subunit RPT4; 26S proteasome regulatory subunit 10B; conserved ATPase domain protein 44; epididymis secretory protein Li 73; proteasome (prosome, macropain) 26S subunit, ATPase, 6; Proteasome 26S subunit ATPase 6; Proteasome subunit p42

            View more View less

            Gene Aliases: 2300001E01Rik; AI451058; CADP44; HEL-S-73; p42; P44; PSMC6; SUG2

            View more View less

            UniProt ID: (Human) P62333, (Mouse) P62334

            View more View less

            Entrez Gene ID: (Human) 5706, (Mouse) 67089

            View more View less

            Function(s)

            protein binding ATP binding ATPase activity TBP-class protein binding protein binding, bridging proteasome-activating ATPase activity nucleotide binding hydrolase activity protease

            Process(es)

            MAPK cascade protein polyubiquitination stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent ubiquitin-dependent protein catabolic process regulation of cellular amino acid metabolic process ER-associated ubiquitin-dependent protein catabolic process anaphase-promoting complex-dependent catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability positive regulation of RNA polymerase II transcriptional preinitiation complex assembly T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Wnt signaling pathway, planar cell polarity pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of proteasomal protein catabolic process protein catabolic process positive regulation of inclusion body assembly
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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