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This antibody is specific to PSMD4.
Immunogen sequence: MVLESTMVC VDNSEYMRNG DFLPTRLQAQ QDAVNIVCHS KTRSNPENNV GLITLANDCE VLTTLTPDTG RILSKLHTVQ PKGKITFCTG IRVAHLALKH RQGKNHKMRI IAFVGSPVED NEKDLVKLAK RLKKEKVNVD IINFGEEEVN TEKLTAFVNT LNGKDGTGSH LVTVPPGPSL ADALISSPIL AGEGGAMLGL GASDFEFGVD PSADPELALA LRVSMEEQRQ RQEEEARRAA AASAAEAGIA TTGTEDSDDA LLKMTISQQE FGRTGLPDLS SMTEEEQIAY AMQMSLQGAE FGQAESADID ASSAMDTSEP AKEEDDYDVM QDPEFLQSVL ENLPGVDPNN EAIRNAMGSL ASQATKDGKK DKKEEDKK (1-377 aa encoded by BC002365)
This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit functions as guanine nucleotide exchange factor. It is reported that this subunit interacts with HIV-1 Tat, and thus it represses the translation of host-cell, but not HIV-1, mRNAs. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 26S proteasome non-ATPase regulatory subunit 4; 26S proteasome regulatory subunit RPN10; 26S proteasome regulatory subunit S5A; AF; angiocidin; anti secretory factor 1; antisecretory factor; Antisecretory factor 1; Multiubiquitin chain-binding protein; multiubiquitin-chain-binding protein; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; RP11-126K1.1; RPN10 homolog; S5a/antisecretory factor protein
Gene Aliases: AF; AF-1; Af1; angiocidin; ASF; MCB1; PSMD4; pUB-R5; Rpn10; S5A
UniProt ID: (Human) P55036, (Mouse) O35226
Entrez Gene ID: (Human) 5710, (Mouse) 19185, (Rat) 83499
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