Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSSLSGKVQT VLGLVEPSKL GRTLTHEHLA MTFDCCYCPP PPCQEAISKE PIVMKNLYWI QKNAYSHKEN LQLNQETEAI KEELLYFKAN GGGALVENTT TGISRDTQTL KRLAEETGVH IISGAGFYVD ATHSSETRAM SVEQLTDVLM NEILHGADGT SIKCGIIGEI GCSWPLTESE RKVLQATAHA QAQLGCPVII HPGRSSRAPF QIIRILQEAG ADISKTVMSH LDRTILDKKE LLEFAQLGCY LEYDLFGTEL LHYQLGPDID MPDDNKRIRR VRLLVEEGCE DRILVAHDIH TKTRLMKYGG HGYSHILTNV VPKMLLRGIT ENVLDKILIE NPKQWLTFK
PTER is a mammalian homolog to bacterial phosphotriesterases, enzymes that hydrolyze phosphotriester-containing organophosphate pesticides. It is expressed primarily in the proximal renal tubules and the gene has been localized in humans to chromosomal band 10p12 by in situ hybridization. PTER, in addition to FTO, MC4R, and NPC1 has recently been shown to be a new risk loci for early-onset and morbid adult obesity in European populations. At least two isoforms of PTER are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hPHRP; Parathion hydrolase-related protein; Phosphotriesterase-related protein; resiniferatoxin-binding, phosphotriesterase-related
Gene Aliases: HPHRP; PTER; RPR-1
UniProt ID: (Human) Q96BW5
Entrez Gene ID: (Human) 9317
Molecular Function:
esterase
hydrolase
metabolite interconversion enzyme
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