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Invitrogen
PTK7 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
PTK7 Antibody (PA5-82070)
Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of PTK7 was observed specifically in Caco-2 cells and in A-549 cells using anti-PTK7 Polyclonal Antibody (Product #PA5-82070) in western blot. The relative expression levels of PTK7 within each cell line is shown using RNA-Seq. {RE... View More
Product Details
PA5-82070
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTK7. Recombinant protein control fragment (Product #RP-101056).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789231
Product Specific Information
Immunogen sequence: TAIVFIKQPS SQDALQGRRA LLRCEVEAPG PVHVYWLLDG APVQDTERRF AQGSSLSFAA VDRLQDSGTF QCVARDDVTG EEARSANASF NIKWIEAGPV VLKHPASEAE IQPQTQVTLR CHIDGHPRPT YQWFR
Target Information
CCK4 may function as a cell adhesion molecule. Although it belongs to the insulin receptor subfamily of the Tyr protein kinases, it likely lacks the catalytic activity of a tyrosine kinase. It may be connected to the pathophysiology of colon carcinomas and/or may represent a tumor progression marker. This Type I membrane protein is highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes, but weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle, and not in colon. It is also expressed in erythroleukemia cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; PTK7 protein tyrosine kinase 7; Tyrosine-protein kinase-like 7
Gene Aliases: CCK-4; CCK4; PTK7
UniProt ID: (Human) Q13308
Entrez Gene ID: (Human) 5754
establishment of planar polarity
ventricular septum development
axis elongation
protein phosphorylation
cell adhesion
signal transduction
positive regulation of neuron projection development
cell migration
actin cytoskeleton reorganization
wound healing
establishment of epithelial cell apical/basal polarity
convergent extension
canonical Wnt signaling pathway
lung-associated mesenchyme development
coronary vasculature development
cellular response to retinoic acid
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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