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Search Thermo Fisher Scientific
Immunogen sequence: KPLARKLMDW EVVSRNSISD DRLETQSLPS RSPPGTPNHR NSTFTQEGTR LRPSSVGHLV DHMVHTSPSE VFVNQRSPSS TQANSIVLES SPSQETPGDG
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signaling downstream of the glutamate receptors through tyrosine dephosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MEG; megakaryocyte phosphatase; megakaryocyte protein-tyrosine phosphatase; protein tyrosine phosphatase MEG1; protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte); Protein-tyrosine phosphatase MEG1; PTP PTPMEG1; PTPase-MEG1; Tyrosine-protein phosphatase non-receptor type 4
Gene Aliases: MEG; PTPMEG; PTPMEG1; PTPN4
UniProt ID: (Human) P29074
Entrez Gene ID: (Human) 5775
Molecular Function:
protein phosphatase
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