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OriGene
PTPRE Monoclonal Antibody (OTI2A9), TrueMAB™
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Product Details
TA501230
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI2A9
Immunogen
Full length human recombinant protein of human PTPRE produced in HEK293T cell.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.79 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein tyrosine phosphatase, receptor type, E; protein tyrosine phosphatase, receptor type, epsilon polypeptide; Protein-tyrosine phosphatase epsilon; PTP epsilon; PTPvarepsilon; Receptor-type tyrosine-protein phosphatase epsilon
Gene Aliases: HPTPE; PTPE; PTPRE; R-PTP-EPSILON
UniProt ID: (Human) P23469
Entrez Gene ID: (Human) 5791
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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