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Immunogen sequence: MILYRLKER FQLSLRQDKE KNQEIHLSPI TLQPALSEAK TVHSMVQPEQ APKVLNVVVD PQGRGAPEIR ATTATSVCPS PFKMKPIGLQ ERRGSNVSLT LDMSSLGNIE PFVSIPTPRE KVAMEYLQSA SRILTRSQLR DVVASSHLLQ SEFMEIPMNF VDPKEIDIPR HGTKNRYKTI LPNPLSRVCL RPKNVTDSLS TYINANYIRG YSGKEKAFIA TQGPMINTVD DFWQMVWQED SPVIVMITKL KEKNEKCVLY WPEKRGIYGK VEVLVISVNE CDNYTIRNLV LKQGSHTQHV KHYWYTSWPD HKTPDSAQPL LQLMLDVEED RLASQGRGPV VVHCSAGIGR TGCFIATSIG CQQLKEEGVV DALSIVCQLR MDRGGMVQTS EQYEFVHHAL CLYESRLSAE TVQ (1-412 aa encoded by BC110900)
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of this gene was reported to be regulated by the nerve growth factor, which suggested the function of this gene in neuronal growth and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ch-1 PTPase; Ch-1PTPase; ECPPT; NC-PTPCOM1; PC12-PTP1; Phosphotyrosine phosphatase 13; protein tyrosine phosphatase Cr1PTPase; protein tyrosine phosphatase PCPTP1; protein tyrosine phosphatase, receptor type, R; protein-tyrosine phosphatase NC-PTPCOM1; Protein-tyrosine phosphatase PCPTP1; Protein-tyrosine-phosphatase SL; protein-tyrosine-phosphatase-SL; R-PTP-R; Receptor-type tyrosine-protein phosphatase R; STEP-like PTPase; Tyrosine phosphatase CBPTP
基因别名: EC-PTP; ECPTP; Gmcp1; mPTP213; PCPTP1; Ptp; PTP-SL; Ptp13; PTPBR7; PTPRQ; PTPRR; RPTPRR
UniProt ID: (Human) Q15256, (Mouse) Q62132, (Rat) O08617
Entrez Gene ID: (Human) 5801, (Mouse) 19279, (Rat) 94202