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            • Primary Antibodies ›
            • PXDN Antibodies

            Invitrogen

            PXDN Polyclonal Antibody

            View all (5) PXDN antibodies
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            Cite PXDN Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            PXDN Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            PXDN Antibody (PA5-121656) in WB

            Western blot analysis of PXDN in recombinant protein. Samples were incubated in polyclonal PXDN antibody (Product # PA5-121656).
            View Product

            PXDN Antibody in Western Blot (WB)

            Product Details

            PA5-121656

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.01-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Gln1285-Ala1475 (Accession Q92626), with N-terminal His Tag
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1.0 mg/mL

            Purification

            Protein A/G

            Storage buffer

            PBS, pH 7.4, with 50% glycerol

            Contains

            0.05% ProClin 300

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2915228

            Target Information

            Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: hsPxd01; Melanoma-associated antigen MG50; p53-responsive gene 2 protein; Peroxidasin 1; Peroxidasin homolog; Vascular peroxidase 1

            View more View less

            Gene Aliases: COPOA; D2S448; D2S448E; KIAA0230; MG50; PRG2; PXD01; PXDN; PXN; VPO; VPO1

            View more View less

            UniProt ID: (Human) Q92626

            View more View less

            Entrez Gene ID: (Human) 7837

            View more View less

            Function(s)

            peroxidase activity interleukin-1 receptor antagonist activity extracellular matrix structural constituent heme binding metal ion binding peroxidase

            Process(es)

            negative regulation of cytokine-mediated signaling pathway immune response response to oxidative stress extracellular matrix organization hydrogen peroxide catabolic process oxidation-reduction process cellular oxidant detoxification
            It has to be done as per old AB suggested Products section.
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            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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