Product References
Self-Renewing CD8+ T-cell Abundance in Blood Associates with Response to Immunotherapy.
Cancer immunology research
Maniar R,Wang PH,Washburn RS,Kratchmarov R,Coley SM,Saqi A,Pan SS,Hu J,Shu CA,Rizvi NA,Henick BS,Reiner SL
53-9003-82 was used in Immunohistochemistry to investigate whether abundance of self-renewing T cells in blood is associated with immunotherapy response.
Fri Feb 03 00:00:00 UTC 2023
Perineural invasion predicts poor survival and cervical lymph node metastasis in oral squamous cell carcinoma.
Medicina oral, patologia oral y cirugia bucal
Martínez-Flores R,Gómez-Soto B,Lozano-Burgos C,Niklander SE,Lopes MA,González-Arriagada WA
53-9003-82 was used in Immunohistochemistry to suggest further investigations to test the combined PNI-TB scoring system in risk stratification models for OSCC.
Fri Sep 01 00:00:00 UTC 2023
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Nature communications
Zhang S,Fang W,Zhou S,Zhu D,Chen R,Gao X,Li Z,Fu Y,Zhang Y,Yang F,Zhao J,Wu H,Wang P,Shen Y,Shen S,Xu G,Wang L,Yan C,Zou X,Chen D,Lv Y
53-9003-82 was used in Immunohistochemistry-immunofluorescence to present the single-cell transcriptomic landscape of synchronously resected pancreatic ductal adenocarcinoma primary tumors and matched liver metastases.
Wed Aug 23 00:00:00 UTC 2023
Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits.
Communications biology
Rodriguez E,Boelaars K,Brown K,Madunić K,van Ee T,Dijk F,Verheij J,Li RJE,Schetters STT,Meijer LL,Le Large TYS,Driehuis E,Clevers H,Bruijns SCM,O'Toole T,van Vliet SJ,Bijlsma MF,Wuhrer M,Kazemier G,Giovannetti E,Garcia-Vallejo JJ,van Kooyk Y
53-9003-82 was used in Flow cytometry/Cell sorting to show mechanisms by which the glyco-code contributes to the tolerogenic microenvironment in PDAC.
Tue Jan 11 00:00:00 UTC 2022
ALCAM: A Novel Surface Marker on EpCAMlow Circulating Tumor Cells.
Biomedicines
Signorelli R,Giret TM,Umland O,Hadisurya M,Lavania S,Charles Richard JL,Middleton A,Boone MM,Ergonul AB,Tao WA,Amirian H,Iliuk A,Khan A,Diaz R,Cortes DB,Garcia-Buitrago M,Charles Jacob HK
53-9003-82 was used in Immunocytochemistry to identify several novel surface biomarkers on CTCs expressed under differing conditions of culture.
Tue Aug 16 00:00:00 UTC 2022
Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature.
Journal for immunotherapy of cancer
Wong-Rolle A,Dong Q,Zhu Y,Divakar P,Hor JL,Kedei N,Wong M,Tillo D,Conner EA,Rajan A,Schrump DS,Jin C,Germain RN,Zhao C
53-9003-82 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin) to develop a novel spatial meta-transcriptomic method simultaneously detecting the expression level of 1,811 host genes and 3 microbe targets (bacteria, fungi, and cytomegalovirus).
Fri Jul 01 00:00:00 UTC 2022
miR-126-3p-loaded small extracellular vesicles secreted by urine-derived stem cells released from a phototriggered imine crosslink hydrogel could enhance vaginal epithelization after vaginoplasty.
Stem cell research & therapy
Xu Y,Qiu Y,Lin Q,Huang C,Li J,Chen L,Xue Z,Wu Q,Wang Y
53-9003-82 was used in Immunohistochemistry to indicate that piGEL-sEVs could be a novel promising approach for enhancing the epithelization of the neovagina after vaginoplasty and provided useful data for understanding the underlying mechanism of the effect of hUSC-sEVs on epithelization.
Sat Jul 23 00:00:00 UTC 2022
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Cell
Chen B,Scurrah CR,McKinley ET,Simmons AJ,Ramirez-Solano MA,Zhu X,Markham NO,Heiser CN,Vega PN,Rolong A,Kim H,Sheng Q,Drewes JL,Zhou Y,Southard-Smith AN,Xu Y,Ro J,Jones AL,Revetta F,Berry LD,Niitsu H,Islam M,Pelka K,Hofree M,Chen JH,Sarkizova S,Ng K,Giannakis M,Boland GM,Aguirre AJ,Anderson AC,Rozenblatt-Rosen O,Regev A,Hacohen N,Kawasaki K,Sato T,Goettel JA,Grady WM,Zheng W,Washington MK,Cai Q,Sears CL,Goldenring JR,Franklin JL,Su T,Huh WJ,Vandekar S,Roland JT,Liu Q,Coffey RJ,Shrubsole MJ,Lau KS
53-9003-82 was used in Flow cytometry/Cell sorting to present a single-cell transcriptomic and imaging atlas of the two most common human colorectal polyps, conventional adenomas and serrated polyps, and their resulting CRC counterparts.
Wed Dec 22 00:00:00 UTC 2021
TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human.
Frontiers in molecular neuroscience
Delalande JM,Nagy N,McCann CJ,Natarajan D,Cooper JE,Carreno G,Dora D,Campbell A,Laurent N,Kemos P,Thomas S,Alby C,Attié-Bitach T,Lyonnet S,Logan MP,Goldstein AM,Davey MG,Hofstra RMW,Thapar N,Burns AJ
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry (Frozen)
Sat Jul 16 00:00:00 UTC 2022
TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human.
Frontiers in molecular neuroscience
Delalande JM,Nagy N,McCann CJ,Natarajan D,Cooper JE,Carreno G,Dora D,Campbell A,Laurent N,Kemos P,Thomas S,Alby C,Attié-Bitach T,Lyonnet S,Logan MP,Goldstein AM,Davey MG,Hofstra RMW,Thapar N,Burns AJ
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry (Frozen)
Sat Jul 16 00:00:00 UTC 2022
Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer.
Virchows Archiv : an international journal of pathology
Tahkola K,Ahtiainen M,Kellokumpu I,Mecklin JP,Laukkarinen J,Laakkonen J,Kenessey I,Jalkanen S,Salmi M,Böhm J
53-9003 was used in Immunohistochemistry to investigate the prognostic significance of CD73 in PDAC.
Mon Feb 01 00:00:00 UTC 2021
Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer.
Virchows Archiv : an international journal of pathology
Tahkola K,Ahtiainen M,Kellokumpu I,Mecklin JP,Laukkarinen J,Laakkonen J,Kenessey I,Jalkanen S,Salmi M,Böhm J
53-9003 was used in Immunohistochemistry to investigate the prognostic significance of CD73 in PDAC.
Mon Feb 01 00:00:00 UTC 2021
Clinical Significance of TWIST-Positive Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma.
Gut and liver
Lee HJ,Kim GH,Park SJ,Kwon CH,Lee MW,Lee BE,Baek DH,I H
53-9003-82 was used in Immunocytochemistry to show investigate the significance between epithelial-mesenchymal transition marker TWIST and patients with esophageal squamous cell carcinoma.
Thu Jul 15 00:00:00 UTC 2021
Clinical Significance of TWIST-Positive Circulating Tumor Cells in Patients with Esophageal Squamous Cell Carcinoma.
Gut and liver
Lee HJ,Kim GH,Park SJ,Kwon CH,Lee MW,Lee BE,Baek DH,I H
53-9003-82 was used in Immunocytochemistry to show investigate the significance between epithelial-mesenchymal transition marker TWIST and patients with esophageal squamous cell carcinoma.
Thu Jul 15 00:00:00 UTC 2021
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Cell reports
Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Cell reports
Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Cell reports
Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Cell reports
Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.
Cell reports
Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Mar 09 00:00:00 UTC 2021
The Extracellular Small Leucine-Rich Proteoglycan Biglycan Is a Key Player in Gastric Cancer Aggressiveness.
Cancers
Pinto F,Santos-Ferreira L,Pinto MT,Gomes C,Reis CA
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry
Tue Mar 16 00:00:00 UTC 2021
Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells.
Cancers
Bartkowiak K,Heidrich I,Kwiatkowski M,Gorges TM,Andreas A,Geffken M,Verpoort K,Müller V,Schlüter H,Pantel K
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Western Blot
Tue Feb 02 00:00:00 UTC 2021
Cysteine-Rich Angiogenic Inducer 61: Pro-Survival Function and Role as a Biomarker for Disseminating Breast Cancer Cells.
Cancers
Bartkowiak K,Heidrich I,Kwiatkowski M,Gorges TM,Andreas A,Geffken M,Verpoort K,Müller V,Schlüter H,Pantel K
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Western Blot
Tue Feb 02 00:00:00 UTC 2021
Dexamethasone Creates a Suppressive Microenvironment and Promotes Aspergillus fumigatus Invasion in a Human 3D Epithelial/Immune Respiratory Model.
Journal of fungi (Basel, Switzerland)
Luvanda MK,Posch W,Noureen A,Lafon E,Zaderer V,Lass-Flörl C,Wilflingseder D
53-9003-82 was used in Flow Cytometry to show that corticosteroids promote enhanced fungal growth and invasion A. fumigatus by creating a suppressive environment affecting both epithelial as well as immune cells.
Thu Mar 18 00:00:00 UTC 2021
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis.
International journal of molecular sciences
Loreth D,Schuette M,Zinke J,Mohme M,Piffko A,Schneegans S,Stadler J,Janning M,Loges S,Joosse SA,Lamszus K,Westphal M,Müller V,Glatzel M,Matschke J,Gebhardt C,Schneider SW,Belczacka I,Volkmer B,Greinert R,Yaspo ML,Harter PN,Pantel K,Wikman H
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry
Tue Jun 29 00:00:00 UTC 2021
CD74 and CD44 Expression on CTCs in Cancer Patients with Brain Metastasis.
International journal of molecular sciences
Loreth D,Schuette M,Zinke J,Mohme M,Piffko A,Schneegans S,Stadler J,Janning M,Loges S,Joosse SA,Lamszus K,Westphal M,Müller V,Glatzel M,Matschke J,Gebhardt C,Schneider SW,Belczacka I,Volkmer B,Greinert R,Yaspo ML,Harter PN,Pantel K,Wikman H
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry
Tue Jun 29 00:00:00 UTC 2021
Establishment of a New Cell Line of Canine Mammary Tumor CMT-1026.
Frontiers in veterinary science
Mei C,Xin L,Liu Y,Lin J,Xian H,Zhang X,Hu W,Xia Z,Wang H,Lyu Y
53-9003-82 was used in Immunohistochemistry to describe a newly established canine cell line, CMT-1026.
Sat Oct 30 00:00:00 UTC 2021
The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells.
Cancer cell
Hu Z,Artibani M,Alsaadi A,Wietek N,Morotti M,Shi T,Zhong Z,Santana Gonzalez L,El-Sahhar S,Carrami EM,Mallett G,Feng Y,Masuda K,Zheng Y,Chong K,Damato S,Dhar S,Campo L,Garruto Campanile R,Soleymani Majd H,Rai V,Maldonado-Perez D,Jones S,Cerundolo V,Sauka-Spengler T,Yau C,Ahmed AA
53-9003-82 was used in Immunohistochemistry (Frozen) to lay the foundation for accurate prognostic and therapeutic stratification of SOC.
Mon Feb 10 00:00:00 UTC 2020
Effective Reconstruction of Functional Urethra Promoted With ICG-001 Delivery Using Core-Shell Collagen/Poly(Llactide-co-caprolactone) [P(LLA-CL)] Nanoyarn-Based Scaffold: A Study in Dog Model.
Frontiers in bioengineering and biotechnology
Zhang K,Fang X,Zhu J,Yang R,Wang Y,Zhao W,Mo X,Fu Q
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunohistochemistry
Mon Sep 28 00:00:00 UTC 2020
Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients.
Frontiers in oncology
Liu HE,Vuppalapaty M,Wilkerson C,Renier C,Chiu M,Lemaire C,Che J,Matsumoto M,Carroll J,Crouse S,Hanft VR,Jeffrey SS,Di Carlo D,Garon EB,Goldman J,Sollier E
53-9003 was used in Immunocytochemistry-immunoflourescence to develop and optimize a workflow for the evaluation of cfDNA and CTCs in NSCLC patients all from one blood sample.
Tue Nov 10 00:00:00 UTC 2020
Detection of EGFR Mutations in cfDNA and CTCs, and Comparison to Tumor Tissue in Non-Small-Cell-Lung-Cancer (NSCLC) Patients.
Frontiers in oncology
Liu HE,Vuppalapaty M,Wilkerson C,Renier C,Chiu M,Lemaire C,Che J,Matsumoto M,Carroll J,Crouse S,Hanft VR,Jeffrey SS,Di Carlo D,Garon EB,Goldman J,Sollier E
53-9003 was used in Immunocytochemistry-immunoflourescence to develop and optimize a workflow for the evaluation of cfDNA and CTCs in NSCLC patients all from one blood sample.
Tue Nov 10 00:00:00 UTC 2020
Direct differentiation of cord blood derived mesenchymal stem cells into keratinocytes without feeder layers and cAMP inducers.
Pakistan journal of medical sciences
Ghauri AK,Wahid M,Mirza T,Uddin JAA
53-9003 was used in Immunocytochemistry-immunoflourescence to isolate umbilical cord blood derived mesenchymal stem (UCB-MSCs), their direct differentiation towards keratinocytes without using feeder layers, cAMP inducers and hormones known for morphological maintenance and proliferation of keratinocytes and characterization of UCB-MSCs.
Fri Apr 15 00:00:00 UTC 2022
PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer.
International journal of molecular sciences
Raimondi L,Raimondi FM,Di Benedetto L,Cimino G,Spinelli GP
53-9003-80 was used in Immunocytochemistry to evaluate PD-L1 expression in patients diagnosed with mCRC and treated with regorafenib.
Sun Sep 20 00:00:00 UTC 2020
PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer.
International journal of molecular sciences
Raimondi L,Raimondi FM,Di Benedetto L,Cimino G,Spinelli GP
53-9003-80 was used in Immunocytochemistry to evaluate PD-L1 expression in patients diagnosed with mCRC and treated with regorafenib.
Sun Sep 20 00:00:00 UTC 2020
Polymorphonuclear MDSCs are enriched in the stroma and expanded in metastases of prostate cancer.
The journal of pathology. Clinical research
Wen J,Huang G,Liu S,Wan J,Wang X,Zhu Y,Kaliney W,Zhang C,Cheng L,Wen X,Lu X
53-9003 was used in Immunohistochemistry-immunofluorescence to reveal the stroma rather than the epithelia of prostate cancer as the major hotbed for PMN-MDSCs and support the role of PMN-MDSCs in the metastatic progression of prostate cancer.
Wed Jul 01 00:00:00 UTC 2020
Temporal and Spatial Heterogeneity of Host Response to SARS-CoV-2 Pulmonary Infection.
medRxiv : the preprint server for health sciences
Desai N,Neyaz A,Szabolcs A,Shih AR,Chen JH,Thapar V,Nieman LT,Solovyov A,Mehta A,Lieb DJ,Kulkarni AS,Jaicks C,Pinto CJ,Juric D,Chebib I,Colvin RB,Kim AY,Monroe R,Warren SE,Danaher P,Reeves JW,Gong J,Rueckert EH,Greenbaum BD,Hacohen N,Lagana SM,Rivera MN,Sholl LM,Stone JR,Ting DT,Deshpande V
53-9003-82 was used in Immunohistochemistry (Paraffin) to demonstrate the intra-pulmonary heterogeneity of SARS-CoV-2 infection.
Sun Aug 02 00:00:00 UTC 2020
Epithelial/Mesenchymal Characteristics and PD-L1 Co-Expression in CTCs of Metastatic Breast Cancer Patients Treated with Eribulin: Correlation with Clinical Outcome.
Cancers
Polioudaki H,Mala A,Gkimprixi E,Papadaki MA,Chantziou A,Tzardi M,Mavroudis D,Agelaki S,Theodoropoulos PA
53-9003 was used in Immunocytochemistry-immunoflourescence to evaluate the co-expression of PD-L1 and epithelial-mesenchymal markers in CTCs from metastatic breast cancer (MBC) patients and to determine if there is any relationship with patients' outcome after eribulin treatment.
Fri Dec 11 00:00:00 UTC 2020
The combination of size-based separation and selection-free technology provides higher circulating tumour cells detection sensitivity than either method alone in patients with metastatic prostate cancer.
BJU international
Dong L,Zhang Z,Smith K,Kuczler MD,Reyes D,Amend SR,Cho YK,Xue W,Pienta KJ
53-9003-82 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Sample Prep to highlight disparities in the positive rates and enumerated circulating tumour cells numbers detected by AccuCyte® -CyteFinder® system (Rarecyte), a selection-free platform, and fluid-assisted separation technology (FAST), a size-based platform.
Wed Jul 01 00:00:00 UTC 2020
SHIFT: speedy histological-to-immunofluorescent translation of a tumor signature enabled by deep learning.
Scientific reports
Burlingame EA,McDonnell M,Schau GF,Thibault G,Lanciault C,Morgan T,Johnson BE,Corless C,Gray JW,Chang YH
53-9003-82 was used in Immunohistochemistry to present a deep learning-based method called speedy histological-to-immunofluorescent translation (SHIFT) which takes histologic images of hematoxylin and eosin (HE)-stained tissue as input, then in near-real time returns inferred virtual immunofluorescence (IF) images that estimate the underlying distribution of the tumor cell marker pan-cytokeratin (panCK).
Thu Oct 15 00:00:00 UTC 2020
A single cell atlas of the human liver tumor microenvironment.
Molecular systems biology
Massalha H,Bahar Halpern K,Abu-Gazala S,Jana T,Massasa EE,Moor AE,Buchauer L,Rozenberg M,Pikarsky E,Amit I,Zamir G,Itzkovitz S
53-9003-82 was used in Tissue fixation to provide a resource for understanding human liver malignancies and may expose potential points of interventions.
Tue Dec 01 00:00:00 UTC 2020
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Nature communications
Desai N,Neyaz A,Szabolcs A,Shih AR,Chen JH,Thapar V,Nieman LT,Solovyov A,Mehta A,Lieb DJ,Kulkarni AS,Jaicks C,Xu KH,Raabe MJ,Pinto CJ,Juric D,Chebib I,Colvin RB,Kim AY,Monroe R,Warren SE,Danaher P,Reeves JW,Gong J,Rueckert EH,Greenbaum BD,Hacohen N,Lagana SM,Rivera MN,Sholl LM,Stone JR,Ting DT,Deshpande V
53-9003-80 was used in Inhibition Assays, Immunohistochemistry (Paraffin) to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
Wed Dec 09 00:00:00 UTC 2020
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Nature communications
Desai N,Neyaz A,Szabolcs A,Shih AR,Chen JH,Thapar V,Nieman LT,Solovyov A,Mehta A,Lieb DJ,Kulkarni AS,Jaicks C,Xu KH,Raabe MJ,Pinto CJ,Juric D,Chebib I,Colvin RB,Kim AY,Monroe R,Warren SE,Danaher P,Reeves JW,Gong J,Rueckert EH,Greenbaum BD,Hacohen N,Lagana SM,Rivera MN,Sholl LM,Stone JR,Ting DT,Deshpande V
53-9003-80 was used in Inhibition Assays, Immunohistochemistry (Paraffin) to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
Wed Dec 09 00:00:00 UTC 2020
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection.
Nature communications
Desai N,Neyaz A,Szabolcs A,Shih AR,Chen JH,Thapar V,Nieman LT,Solovyov A,Mehta A,Lieb DJ,Kulkarni AS,Jaicks C,Xu KH,Raabe MJ,Pinto CJ,Juric D,Chebib I,Colvin RB,Kim AY,Monroe R,Warren SE,Danaher P,Reeves JW,Gong J,Rueckert EH,Greenbaum BD,Hacohen N,Lagana SM,Rivera MN,Sholl LM,Stone JR,Ting DT,Deshpande V
53-9003-80 was used in Inhibition Assays, Immunohistochemistry (Paraffin) to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
Wed Dec 09 00:00:00 UTC 2020
Evaluation of Microfluidic Ceiling Designs for the Capture of Circulating Tumor Cells on a Microarray Platform.
Advanced biosystems
Liu HY,Koch C,Haller A,Joosse SA,Kumar R,Vellekoop MJ,Horst LJ,Keller L,Babayan A,Failla AV,Jensen J,Peine S,Keplinger F,Fuchs H,Pantel K,Hirtz M
53-9003-82 was used in Immunocytochemistry to underline the importance of evaluating rational design rules for microfluidic devices based on theoretical models by application-specific experiments.
Sat Feb 01 00:00:00 UTC 2020
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer.
Scientific data
Rashid R,Gaglia G,Chen YA,Lin JR,Du Z,Maliga Z,Schapiro D,Yapp C,Muhlich J,Sokolov A,Sorger P,Santagata S
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunocytochemistry
Tue Dec 17 00:00:00 UTC 2019
Loss of the Krüppel-like factor 4 tumor suppressor is associated with epithelial-mesenchymal transition in colorectal cancer.
Journal of cancer metastasis and treatment
Agbo KC,Huang JZ,Ghaleb AM,Williams JL,Shroyer KR,Bialkowska AB,Yang VW
53-9003-82 was used in Immunohistochemistry to suggest that the loss of KLF4 expression is a potentially significant indicator of EMT in CRC.
Fri Apr 15 00:00:00 UTC 2022
Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors.
Cancers
Janning M,Kobus F,Babayan A,Wikman H,Velthaus JL,Bergmann S,Schatz S,Falk M,Berger LA,Böttcher LM,Päsler S,Gorges TM,O'Flaherty L,Hille C,Joosse SA,Simon R,Tiemann M,Bokemeyer C,Reck M,Riethdorf S,Pantel K,Loges S
53-9003-82 was used in Immunocytochemistry to test an epitope-independent method (ParsortixTM system) and utilized it to assess PD-L1 expression of CTCs from NSCLC patients.
Mon Jun 17 00:00:00 UTC 2019
Cell signaling heterogeneity is modulated by both cell-intrinsic and -extrinsic mechanisms: An integrated approach to understanding targeted therapy.
PLoS biology
Kim E,Kim JY,Smith MA,Haura EB,Anderson ARA
53-9003 was used in Proximity Ligation Assay to present a mathematical framework that addresses the impact of signaling heterogeneity on targeted cancer therapy outcomes.
Thu Mar 01 00:00:00 UTC 2018
Screening Circulating Tumor Cells as a Noninvasive Cancer Test in 3388 Individuals from High-Risk Groups (ICELLATE2).
Disease markers
Castro J,Sanchez L,Nuñez MT,Lu M,Castro T,Sharifi HR,Ericsson C
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunofluorescence
Mon Oct 22 00:00:00 UTC 2018
Development of lacrimal gland spheroids for lacrimal gland tissue regeneration.
Journal of tissue engineering and regenerative medicine
Massie I,Spaniol K,Barbian A,Geerling G,Metzger M,Schrader S
53-9003-82 was used in Immunohistochemistry to combine epithelial cells with endothelial cells and mesenchymal stem cells (MSCs) to form a 3D functional unit.
Sun Apr 01 00:00:00 UTC 2018
Inhibition of CXCR4 by MicroRNA-1192 Reduces the Activation of Th17 Cells and Expression of Inflammation Factors in a Mouse Model of Vulvovaginal Candidiasis.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Liu J,Wang HZ,Sun Y
53-9003-82 was used in Immunohistochemistry to provide significant evidence that miR-1192 could directly development and progression of VVC by restraining the CXCR4 gene in the VVC mice.
Fri Nov 09 00:00:00 UTC 2018
The VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner.
Nature communications
Agerbæk MØ,Bang-Christensen SR,Yang MH,Clausen TM,Pereira MA,Sharma S,Ditlev SB,Nielsen MA,Choudhary S,Gustavsson T,Sorensen PH,Meyer T,Propper D,Shamash J,Theander TG,Aicher A,Daugaard M,Heeschen C,Salanti A
53-9003 was used in Immunocytochemistry-immunoflourescence to develop a method for circulating tumour cell isolation based on the specific binding of the malaria rVAR2 protein to oncofoetal chondroitin sulfate.
Thu Aug 16 00:00:00 UTC 2018
Betamethasone prevents human rhinovirus- and cigarette smoke- induced loss of respiratory epithelial barrier function.
Scientific reports
Waltl EE,Selb R,Eckl-Dorna J,Mueller CA,Cabauatan CR,Eiwegger T,Resch-Marat Y,Niespodziana K,Vrtala S,Valenta R,Niederberger V
53-9003 was used in Flow cytometry/Cell sorting to identify cigarette smoke extract and house dust mite extract have a synergetic damaging effect on the respiratory epithelial barrier function and that betamethason protects against human rhinovirus and cigarette smoke extract damage.
Tue Jun 26 00:00:00 UTC 2018
Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b.
Diabetes
Sun SF,Tang PMK,Feng M,Xiao J,Huang XR,Li P,Ma RCW,Lan HY
53-9003-82 was used in Immunohistochemistry to study a novel Smad3-dependent long noncoding RNA (lncRNA) Erbb4-IR in the development of type 2 diabetic nephropathy (T2DN) in db/db mice.
Sun Apr 01 00:00:00 UTC 2018
Microscale Laminar Vortices for High-Purity Extraction and Release of Circulating Tumor Cells.
Methods in molecular biology (Clifton, N.J.)
Hur SC,Che J,Di Carlo D
53-9003-82 was used in Immunocytochemistry-immunofluorescence to describe how to fabricate the High-Throughput Vortex Chip (Vortex-HT) and to process diluted whole blood for CTC collection.
Fri Apr 27 00:00:00 UTC 2018
Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection.
NPJ genomic medicine
Liu HE,Triboulet M,Zia A,Vuppalapaty M,Kidess-Sigal E,Coller J,Natu VS,Shokoohi V,Che J,Renier C,Chan NH,Hanft VR,Jeffrey SS,Sollier-Christen E
53-9003 was used in Immunocytochemistry-immunoflourescence to demonstrate the feasibility of a workflow for clinically relevant monitoring of tumour genetics in real time and over the course of a patient's therapy using circulating tumour cells.
Thu Oct 01 00:00:00 UTC 2020
Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rg mice.
NPJ breast cancer
Donnenberg VS,Huber A,Basse P,Rubin JP,Donnenberg AD
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunofluorescence
Tue Nov 08 00:00:00 UTC 2022
Neither epithelial nor mesenchymal circulating tumor cells isolated from breast cancer patients are tumorigenic in NOD-scid Il2rg mice.
NPJ breast cancer
Donnenberg VS,Huber A,Basse P,Rubin JP,Donnenberg AD
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunofluorescence
Tue Nov 08 00:00:00 UTC 2022
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high-resolution intact circuit mapping and phenotyping.
Nature protocols
Treweek JB,Chan KY,Flytzanis NC,Yang B,Deverman BE,Greenbaum A,Lignell A,Xiao C,Cai L,Ladinsky MS,Bjorkman PJ,Fowlkes CC,Gradinaru V
53-9003 was used in Immunohistochemistry to develop a set of tissue fixation-embedding, detergent-clearing and staining protocols to transform excised organs and whole organisms into optically transparent samples without compromising their cellular architecture or endogenous fluorescence.
Sun Nov 01 00:00:00 UTC 2015
Mutagenic, surviving and tumorigenic effects of follicular fluid in the context of p53 loss: initiation of fimbria carcinogenesis.
Carcinogenesis
Huang HS,Chu SC,Hsu CF,Chen PC,Ding DC,Chang MY,Chu TY
53-9003 was used in Immunocytochemistry to examine the mutagenic and tumourigenic activities of human pre-ovulatory follicular fluids.
Sun Nov 01 00:00:00 UTC 2015
Modified Leukocyte Filter Removes Tumor Cells from the Salvaged Blood.
PloS one
Mei K,Du L,Yan M,Zhang Z,Zhang F,Gong L,Sun K,Zhang J,Tang Y,Jiang C,Liu J
53-9003 was used in Immunocytochemistry to evaluate the application of modified leukocyte depletion filter for once-surgery, and suggest the potential clinical application for blood cancers treatment.
Mon Mar 21 00:00:00 UTC 2016
A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages.
Nature cell biology
Lu H,Clauser KR,Tam WL,Fröse J,Ye X,Eaton EN,Reinhardt F,Donnenberg VS,Bhargava R,Carr SA,Weinberg RA
53-9003 was used in Immunohistochemistry on paraffin embedded tissues to investigate the interactions between cancer stem cells and their surrounding microenvironment.
Sat Nov 01 00:00:00 UTC 2014
Tyrosine phosphoproteomics identifies both codrivers and cotargeting strategies for T790M-related EGFR-TKI resistance in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
Yoshida T,Zhang G,Smith MA,Lopez AS,Bai Y,Li J,Fang B,Koomen J,Rawal B,Fisher KJ,Chen YA,Kitano M,Morita Y,Yamaguchi H,Shibata K,Okabe T,Okamoto I,Nakagawa K,Haura EB
53-9003 was used in Immunohistochemistry-immunofluorescence to identify codrivers of resistance along with T790M and support further studies of irreversible or T790M-selective EGFR inhibitors combined with dasatinib in patients with non-small cell lung cancer with acquired T790M.
Fri Aug 01 00:00:00 UTC 2014
In vitro validation of an ultra-sensitive scanning fluorescence microscope for analysis of circulating tumor cells.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
Hillig T,Nygaard AB,Nekiunaite L,Klingelhöfer J,Sölétormos G
53-9003-82 was used in Flow cytometry/Cell sorting to validate a method of ultra-sensitive scanning fluorescence microscope for analysis of circulating tumour cells.
Sun Jun 01 00:00:00 UTC 2014
Flow cytometric determination of stem/progenitor content in epithelial tissues: an example from nonsmall lung cancer and normal lung.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Donnenberg VS,Landreneau RJ,Pfeifer ME,Donnenberg AD
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Immunofluorescence
Tue Jan 01 00:00:00 UTC 2013
Binding and isolation of tumor cells in biological media with perfluorocarbon microbubbles.
Methods (San Diego, Calif.)
Shi G,Cui W,Mukthavaram R,Liu YT,Simberg D
Sun Dec 01 00:00:00 UTC 2013
Isolation of rare tumor cells from blood cells with buoyant immuno-microbubbles.
PloS one
Shi G,Cui W,Benchimol M,Liu YT,Mattrey RF,Mukthavaram R,Kesari S,Esener SC,Simberg D
53-9003 was used in Immunofluorescence to report a novel method for isolation of rare tumor cells from excess of blood cells using gas-filled buoyant immuno-microbubbles.
Thu Sep 12 00:00:00 UTC 2013
KIT (CD117) expression in a subset of non-small cell lung carcinoma (NSCLC) patients.
PloS one
Donnenberg AD,Zimmerlin L,Landreneau RJ,Luketich JD,Donnenberg VS
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Jul 23 00:00:00 UTC 2013
KIT (CD117) expression in a subset of non-small cell lung carcinoma (NSCLC) patients.
PloS one
Donnenberg AD,Zimmerlin L,Landreneau RJ,Luketich JD,Donnenberg VS
Published figure using Pan Cytokeratin monoclonal antibody (Product # 53-9003-82) in Flow Cytometry
Tue Jul 23 00:00:00 UTC 2013
