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NeoBiotechnologies
Pan-HLA-II (DP, DQ, DR) Recombinant Rabbit Monoclonal Antibody (HLA-Pan/9268R)
Product Details
RBM8-9268-P1ABX
Product Specifications
Species Reactivity
All
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HLA-Pan/9268R
Immunogen
Priess human B cell line
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
Positive Control:Ramos or Raji cells. Human tonsil or lymph node.
Cellular Location: Cell surface
Target Information
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ75017; FLJ76359; HLA-D; HLA-DQ; HLA-DR; MHC Class 2; MHC class II; MHC HLA-D; MHC II HLA; XXbac-BPG161M6.1
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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