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            • Primary Antibodies ›
            • Pan Pax Antibodies

            Proteintech

            Pan-PAX Polyclonal Antibody

            5 References
            Datasheet
            Protocols
            Questions & Answers
            Catalog # 21383-1-AP
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            Price (USD)
            492.00
            150 µL
             
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            Cite Pan-PAX Polyclonal Antibody

            • Antibody Testing Data (10)
            Application
            Pan-PAX Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 10

            Pan-PAX Antibody (21383-1-AP) in ICC/IF

            Immunofluorescent analysis of ( -20°C Ethanol ) fixed SKOV-3 cells using 21383-1-AP (Pan-PAX antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).
            View Product

            Pan-PAX Antibody in Immunocytochemistry (ICC/IF)
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Pan-PAX Antibody in Western Blot (WB)
            Pan-PAX Antibody in Western Blot (WB)
            Pan-PAX Antibody in Immunoprecipitation (IP)

            Product Details

            21383-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:500-1:2,000
            -

            Immunohistochemistry (IHC)

            -
            View 3 publications 3 publications

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:500
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:500
            View 2 publications 2 publications

            Immunoprecipitation (IP)

            0.5-4.0 µg
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Human, Mouse, Pig

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Pan-PAX Fusion Protein Ag16018

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.35 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            This antibody is a Pan-PAX antibody.

            Target Information

            This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: Aniridia type II protein; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; Dickie's small eye; homeodomain protein PAX3; HuP1; HuP2; HuP48; Oculorhombin; optic disc coloboma; paired box gene 1; paired box gene 2; paired box gene 3; paired box gene 4; paired box gene 5; paired box gene 6; paired box gene 7; paired box gene 8; paired box gene 9; Paired box homeotic gene 1; paired box homeotic gene 2; paired box homeotic gene 3; paired box homeotic gene 5; paired box homeotic gene 6; paired box homeotic gene 7; paired box homeotic gene-6; Paired box protein Pax-1; Paired box protein Pax-2; Paired box protein Pax-3; Paired box protein Pax-4; Paired box protein Pax-5; Paired box protein Pax-6; Paired box protein Pax-7; Paired box protein Pax-8; Paired box protein Pax-9; paired box transcription factor PAX7; paired domain gene 3; paired domain gene 4; paired domain gene 5; paired domain gene 7; paired domain gene 8; paired domain gene 9; paired domain gene HuP2; paired domain gene HuP48; Pax-8 protein; PAX3/FKHR fusion; Pax5 variant 1; Pax5 variant 2; PAX7 transcriptional factor; pax9 {ECO:0000312|EMBL:BAE79272.1}; small eye; transcription factor PAX 5; wavy tail

            View more View less

            Gene Aliases: 1500038E17Rik; AEY11; ALL3; AN; AN2; BSAP; CDHS; D11S812E; Dey; EBB-1; FSGS7; FVH1; Gsfaey11; hbs; hunchback; HUP1; HUP2; HUP48; KLP; KPD; MGDA; MODY9; OFC2; Opdc; PAPRS; Pax-1; Pax-2; Pax-3; Pax-4; Pax-5; Pax-6; Pax-7; Pax-8; Pax-9; PAX1; PAX2; PAX3; Pax4; PAX5; PAX6; PAX7; PAX7B; PAX8; PAX9; RGD1564360; RGD1565236; RMS2; Sey; Sp; splotch; STHAG3; un; undulated; WAGR; WS1; WS3; wt

            View more View less

            UniProt ID: (Human) P15863, (Human) Q02962, (Human) P23760, (Human) Q02548, (Human) P26367, (Human) P23759, (Human) Q06710, (Human) P55771, (Mouse) P09084, (Mouse) P32114, (Mouse) P24610, (Rat) O88436, (Mouse) P32115, (Mouse) Q02650, (Mouse) P63015, (Rat) P63016, (Mouse) P47239, (Mouse) Q00288, (Rat) P51974, (Rat) Q2L4T2, (Mouse) P47242

            View more View less

            Entrez Gene ID: (Human) 5075, (Human) 5076, (Human) 5077, (Human) 5078, (Human) 5079, (Human) 5080, (Human) 5081, (Human) 7849, (Human) 5083, (Rat) 311505, (Mouse) 18503, (Rat) 293992, (Mouse) 18504, (Rat) 114502, (Mouse) 18505, (Rat) 83630, (Mouse) 18506, (Rat) 500453, (Mouse) 18507, (Mouse) 18508, (Rat) 25509, (Rat) 500574, (Mouse) 18509, (Mouse) 18510, (Rat) 81819, (Rat) 362741, (Mouse) 18511

            View more View less

            Function(s)

            DNA binding transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding protein binding transcription factor binding superoxide-generating NADPH oxidase activity transcription regulatory region DNA binding sequence-specific DNA binding HMG box domain binding RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding ubiquitin-protein transferase activity protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding co-SMAD binding R-SMAD binding transcription factor activity, RNA polymerase II core promoter sequence-specific thyroid-stimulating hormone receptor activity RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding C2H2 zinc finger domain binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding double-stranded DNA binding AT DNA binding molecular_function homeodomain transcription factor

            Process(es)

            skeletal system development somitogenesis transcription from RNA polymerase II promoter cell proliferation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation positive regulation of transcription from RNA polymerase II promoter thymus development parathyroid gland development bone morphogenesis sclerotome development urogenital system development branching involved in ureteric bud morphogenesis cell fate determination mesonephros development neural tube closure optic cup morphogenesis involved in camera-type eye development mesenchymal to epithelial transition involved in metanephros morphogenesis retinal pigment epithelium development transcription, DNA-templated axonogenesis mesodermal cell fate specification aging visual perception glial cell differentiation optic nerve development optic nerve morphogenesis optic nerve structural organization vestibulocochlear nerve formation response to nutrient levels regulation of metanephros size ureter maturation pronephric field specification inner ear morphogenesis camera-type eye development negative regulation of apoptotic process negative regulation of programmed cell death negative regulation of cysteine-type endopeptidase activity involved in apoptotic process protein kinase B signaling negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated negative regulation of cytolysis pronephros development brain morphogenesis stem cell differentiation positive regulation of epithelial cell proliferation oxidation-reduction process mesenchymal to epithelial transition optic chiasma development cellular response to hydrogen peroxide cellular response to retinoic acid cellular response to glucose stimulus cellular response to epidermal growth factor stimulus metanephric mesenchyme development positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis metanephric mesenchymal cell differentiation nephric duct formation ureter development metanephric collecting duct development metanephric epithelium development metanephric distal convoluted tubule development metanephric nephron tubule formation positive regulation of metanephric glomerulus development negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis regulation of metanephric nephron tubule epithelial cell differentiation reactive oxygen species metabolic process cochlea development cochlea morphogenesis positive regulation of branching involved in ureteric bud morphogenesis negative regulation of mesenchymal cell apoptotic process involved in metanephros development negative regulation of apoptotic process involved in metanephric collecting duct development negative regulation of apoptotic process involved in metanephric nephron tubule development negative regulation of reactive oxygen species metabolic process positive regulation of metanephric DCT cell differentiation positive regulation of optic nerve formation apoptotic process nervous system development muscle organ development sensory perception of sound organ morphogenesis neural crest formation negative regulation of transcription from RNA polymerase II promoter circadian rhythm cell differentiation endocrine pancreas development response to drug positive regulation of cell differentiation response to cAMP retina development in camera-type eye humoral immune response multicellular organism development spermatogenesis lateral ventricle development cerebral cortex development adult behavior skeletal muscle cell differentiation embryonic cranial skeleton morphogenesis negative regulation of histone H3-K9 methylation establishment of mitotic spindle orientation blood vessel development eye development neuron migration negative regulation of protein phosphorylation positive regulation of neuroblast proliferation lens development in camera-type eye type B pancreatic cell differentiation pancreatic A cell development smoothened signaling pathway axon guidance central nervous system development salivary gland morphogenesis response to wounding regulation of asymmetric cell division dorsal/ventral axis specification positive regulation of gene expression protein ubiquitination oligodendrocyte cell fate specification cerebral cortex regionalization forebrain anterior/posterior pattern specification forebrain dorsal/ventral pattern formation commitment of neuronal cell to specific neuron type in forebrain forebrain-midbrain boundary formation regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment pituitary gland development signal transduction involved in regulation of gene expression keratinocyte differentiation regulation of cell migration positive regulation of epithelial cell differentiation lacrimal gland development protein localization to organelle eye photoreceptor cell development glucose homeostasis negative regulation of neuron differentiation regulation of timing of cell differentiation embryonic camera-type eye morphogenesis neuron fate commitment astrocyte differentiation negative regulation of epithelial cell proliferation negative regulation of neurogenesis iris morphogenesis cornea development in camera-type eye negative regulation of neural precursor cell proliferation chromatin remodeling anatomical structure morphogenesis regulation of cell fate commitment skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation kidney development sulfur compound metabolic process thyroid gland development thyroid-stimulating hormone signaling pathway regulation of apoptotic process cellular response to gonadotropin stimulus otic vesicle development metanephric comma-shaped body morphogenesis metanephric S-shaped body morphogenesis positive regulation of thyroid hormone generation regulation of thyroid-stimulating hormone secretion endoderm development odontogenesis regulation of odontogenesis face morphogenesis cellular response to growth factor stimulus pattern specification process regulation of transcription, DNA-templated metanephros development ureteric bud development positive regulation of cell proliferation pancreas development regulation of programmed cell death animal organ development paramesonephric duct development cellular response to mechanical stimulus renal system development mesonephric tubule development mesonephric tubule formation mesonephric duct development ureter morphogenesis neural crest cell migration heart development regulation of somitogenesis cell migration neural tube development gliogenesis developmental pigmentation skeletal muscle organ development mammary gland specification cardiac muscle cell differentiation regulation of cell differentiation epithelial cell development pancreatic A cell differentiation regulation of transcription from RNA polymerase II promoter brain development negative regulation of cell proliferation anterior/posterior pattern specification dorsal/ventral pattern formation regulation of gene expression regulation of neuron projection development pallium development rhombomere morphogenesis olfactory bulb development telencephalon regionalization interkinetic nuclear migration forebrain development hindbrain development positive regulation of cell fate specification cell fate commitment regulation of neuron differentiation regulation of neurogenesis neural precursor cell proliferation positive regulation of glucagon secretion insulin metabolic process positive regulation of neuron migration spinal cord development cerebellum development cellular response to insulin stimulus cellular response to drug cellular response to fibroblast growth factor stimulus response to ethanol cellular response to prostaglandin E stimulus skeletal muscle tissue development biological_process
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