Product References
Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses.
Immunity
Xu K,Yin N,Peng M,Stamatiades EG,Chhangawala S,Shyu A,Li P,Zhang X,Do MH,Capistrano KJ,Chou C,Leslie CS,Li MO
A-21328 was used in Immunocytochemistry-immunoflourescence to show that Warburg metabolism augments glycolytic ATP production, fueling a PI3K-centered positive feedback regulatory circuit that drives effector T cell responses.
Tue May 11 00:00:00 UTC 2021
Delivery of membrane impermeable molecules to primary mouse T lymphocytes.
STAR protocols
Xu K,Li MO
A-21328 was used in Immunocytochemistry to demonstrate a protocol for delivery of membrane impermeable molecules to primary mouse T lymphocytes using the pore-forming toxin streptolysin-O.
Fri Sep 17 00:00:00 UTC 2021
Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway.
Cell reports
Chen YH,Kratchmarov R,Lin WW,Rothman NJ,Yen B,Adams WC,Nish SA,Rathmell JC,Reiner SL
A-21328 was used in Immunocytochemistry-immunoflourescence to show that receptor-associated class I phosphatidylinositol 3-kinase (PI3K) signaling activity, indexed by phosphatidylinositol (3,4,5)-trisphosphate (PIP3) staining, is spatially restricted to the microtubule-organizing center and subsequently to one pole of the mitotic spindle in activated T and B lymphocytes.
Tue Jan 23 00:00:00 UTC 2018
BCR-ABL inactivates cytosolic PTEN through Casein Kinase II mediated tail phosphorylation.
Cell cycle (Georgetown, Tex.)
Morotti A,Panuzzo C,Crivellaro S,Carrà G,Fava C,Guerrasio A,Pandolfi PP,Saglio G
Published figure using Phosphatidylinositol 3,4,5-trisphosphate monoclonal antibody (Product # A-21328) in Immunofluorescence
Mon Dec 28 00:00:00 UTC 2015
Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia.
Blood
Shehata M,Schnabl S,Demirtas D,Hilgarth M,Hubmann R,Ponath E,Badrnya S,Lehner C,Hoelbl A,Duechler M,Gaiger A,Zielinski C,Schwarzmeier JD,Jaeger U
A-21328 was used in immunocytochemistry to assess the molecular mechanisms of chronic lymphocytic leukemia cell survival
Thu Oct 07 00:00:00 UTC 2010
Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration.
Developmental dynamics : an official publication of the American Association of Anatomists
Mapp OM,Wanner SJ,Rohrschneider MR,Prince VE
A-21328 was used in immunohistochemistry to describe the cellular dynamics of migrating facial neurons
Tue Jun 01 00:00:00 UTC 2010
EHD1 and Eps15 interact with phosphatidylinositols via their Eps15 homology domains.
The Journal of biological chemistry
Naslavsky N,Rahajeng J,Chenavas S,Sorgen PL,Caplan S
A-21328 was used in immunocytochemistry and western blot to investigate EHD1's interaction with phosphatidylinositols
Fri Jun 01 00:00:00 UTC 2007
Cross-talk between CD14 and complement receptor 3 promotes phagocytosis of mycobacteria: regulation by phosphatidylinositol 3-kinase and cytohesin-1.
Journal of immunology (Baltimore, Md. : 1950)
Sendide K,Reiner NE,Lee JS,Bourgoin S,Talal A,Hmama Z
A-21328 was used in immunocytochemistry to study factors that regulate the phagocytosis of Mycobacterium bovis bacillus Calmette-Guerin
Fri Apr 01 00:00:00 UTC 2005