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Product Details
BS-3001R-HRP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide derived from human Acinus around the phosphorylation site of Ser1180.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
Target Information
ACINUS (apoptotic chromatin condensation inducer in the nucleus) is an induced of chromatin condensation. ACINUS is cleaved by caspase-3 and an additional unknown protease generating a small active peptide, p17, which causes chromatin condensation in vitro when it is added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells. ACINUS is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acinus; Apoptotic chromatin condensation inducer in the nucleus; DKFZp667N107; functional spliceosome-associated protein 152
Gene Aliases: 2610036I19Rik; 2610510L13Rik; ACIN1; ACINUS; acinusL; acinusS; ACN; C79325; fSAP152; KIAA0670; mKIAA0670
UniProt ID: (Human) Q9UKV3, (Mouse) Q9JIX8
Entrez Gene ID: (Human) 22985, (Mouse) 56215
positive regulation of defense response to virus by host
mRNA processing
cellular component disassembly involved in execution phase of apoptosis
RNA splicing
erythrocyte differentiation
apoptotic chromosome condensation
positive regulation of monocyte differentiation
mitophagy in response to mitochondrial depolarization
xenophagy
apoptotic process
regulation of autophagy
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of mRNA splicing, via spliceosome
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