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Invitrogen
Phospho-EphB Pan (Tyr600, Tyr602, Tyr614, Tyr596) Polyclonal Antibody
Product Details
PA5-64578
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human EPHB1/2/3/4 (Phospho-Tyr600/602/614/596)
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2662980
Product Specific Information
Phospho-EphB Pan (Tyr600, Tyr602, Tyr614, Tyr596) Polyclonal Antibody detects endogenous levels of EphB Pan only when phosphorylated at Tyr600, Tyr602, Tyr614, Tyr596.
Target Information
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Developmental kinase 2; Developmental kinase 5; Developmentally-regulated Eph-related tyrosine kinase; EK2; EK5; EK6; ELK; ELK-related protein tyrosine kinase; ELK-related tyrosine kinase; Embryonic kinase 2; Eph receptor B2 (ELK-related protein tyrosine kinase); EPH receptor B4; EPH tyrosine kinase 2; EPH tyrosine kinase 3; EPH-like kinase 2; EPH-like kinase 5; EPH-like kinase 6; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; Ephrin B1; Ephrin B2; Ephrin B3; Ephrin B4; ephrin receptor EphB4; Ephrin type-B receptor 1; Ephrin type-B receptor 2; Ephrin type-B receptor 3; Ephrin type-B receptor 4; EphrinB1; EphrinB2; EphrinB3; EphrinB4; HEK-6; Hepatoma transmembrane kinase; human embryo kinase 2; mDK-2; mDK-5; MGC87492; NET; Neural kinase; Neuronally-expressed EPH-related tyrosine kinase; Nuk receptor tyrosine kinase; protein-tyrosine kinase HEK5; Renal carcinoma antigen NY-REN-47; soluble EPHB1 variant 1; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; Tyrosine kinase MYK-1; Tyrosine-protein kinase receptor EPH-2; Tyrosine-protein kinase receptor EPH-3; tyrosine-protein kinase receptor HTK; Tyrosine-protein kinase receptor SEK-3; Tyrosine-protein kinase receptor SEK-4; Tyrosine-protein kinase TYRO11; Tyrosine-protein kinase TYRO5; Tyrosine-protein kinase TYRO6
Gene Aliases: 9330129L11; AI042935; AW456895; AW488255; C130099E04Rik; CAPB; Cek10; Cek5; Cek6; DRT; EK2; EK5; ELK; Elkh; ENSMUSG00000074119; EPHB1; EPHB2; EPHB3; EPHB4; EPHT2; EPHT3; Epth2; EPTH3; ERK; ETECK; ETK2; HEK2; HEK5; HEK6; HTK; MDK2; MDK5; MYK1; NET; Nuk; PCBC; Prkm5; Qek5; RGD1564232; Sek3; Sek4; TYRO11; TYRO5; TYRO6
UniProt ID: (Human) P54762, (Human) P29323, (Human) P54753, (Human) P54760, (Rat) P09759, (Mouse) Q8CBF3, (Mouse) P54763, (Mouse) P54754, (Mouse) P54761
Entrez Gene ID: (Human) 2047, (Human) 2048, (Human) 2049, (Human) 2050, (Rat) 24338, (Mouse) 270190, (Mouse) 13844, (Rat) 313633, (Mouse) 13845, (Rat) 287989, (Rat) 686310, (Mouse) 13846
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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