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Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) Antibody (PA5-118672) in ICC/IF
Immunocytochemical analysis of Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) in HepG2 cells using a Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) polyclonal antibody (Product # PA5-118672). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjug... View More
Product Details
PA5-118672
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human FGFR1/2 around the phosphorylation site of Tyr730/733.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2903172
Target Information
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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