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7TM Antibodies
Phospho-Formylpeptide Receptor 2 (Thr346) Polyclonal Antibody
Application
FIGURE: 1 / 1
Phospho-Formylpeptide Receptor 2 (Thr346) Antibody (7TM0223B) in WB
Agonist-induced Threonine346 phosphorylation of FPR2 Receptor. Upper panel, HEK293 cells stably expressing the FPR2-Receptor (FPR2) were either not exposed or exposed to 1 µM of specific FPR-Receptor Agonist fMet-Leu-Phe for 30 minutes. Cells were lysed and immunoblotted with the anti-pT346-FPR2 antibody (7TM0223B) at a dilution of 1:1,000. Lower panel, blot was stripped and reprobed with an phosphorylation... View More
Product Details
7TM0223B
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphopeptide derived from human FPR2 around the phosphorylation site Thr346.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
Dulbecco's PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Formyl peptide receptor 2 (FPR2) is a low affinity receptor for N-formyl-methionyl peptides. Binding of FMLP to FPR2 causes activation of neutrophils. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMLP-R-I; FMLP-related receptor I; fMLPR1; Formyl peptide receptor-like 1; FPR-like 1; Fpr-rs1; Fprl-1; HM63; Lipoxin A4 receptor; lipoxin A4 receptor (formyl peptide receptor related); Lipoxin receptor; LXA4 receptor; N-formyl peptide receptor 2; RFP
Gene Aliases: ALXR; FMLP-R-II; FMLPX; FPR2; FPR2A; FPRH1; FPRH2; FPRL1; HM63; LXA4R
UniProt ID: (Human) P25090
Entrez Gene ID: (Human) 2358
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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