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Invitrogen
Phospho-NHE3 (Ser552) Monoclonal Antibody (14D5), DyLight™ 650
Product Details
MA5-16093
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Marsupial,
Mouse,
Non-human primate,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
14D5
Immunogen
Synthetic peptide made to a region surrounding the Serine 552 portion of the rat protein.
Conjugate
Excitation/Emission Max
651/673 nm
View spectra
Form
Liquid
Concentration
2 mg/mL
Purification
Protein G
Storage buffer
50mM sodium borate
Contains
no preservative
Storage conditions
4° C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11152216
Target Information
NHE3 (also known as SLC9A3 - Sodium/hydrogen exchanger 3) is a member of the sodium/hydrogen exchanger family that plays a crucial role in acid-base and volume homeostasis by mediating the majority of sodium and bicarbonate reabsorption in the proximal tubule of the kidney. Mutations in the gene can lead to Diarrhea 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC126718; MGC126720; Na(+)/H(+) exchanger 3; Na+/H+ exchanger homolog; Na+/H+ exchanger isoform 3; membrane ion exchange protein; Na/H exchanger 3; NHE-3; NHE-3 antibody; plasma membrane ion transport protein; SLC9A3 antibody; sodium/hydrogen exchanger; Sodium/hydrogen exchanger 3; Solute carrier family 9 (sodium/hydrogen exchanger 3), antiporter 3, Na+/H+ (amiloride insensitive); solute carrier family 9 (sodium/hydrogen exchanger), isoform 3; solute carrier family 9 (sodium/hydrogen exchanger), member 3; Solute carrier family 9 member 3; solute carrier family 9, member 3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
Gene Aliases: 9030624O13Rik; AI930210; DIAR8; NHE-3; NHE3; SLC9A3
UniProt ID: (Rabbit) P26432, (Human) P48764, (Mouse) G3X939, (Rat) P26433
Entrez Gene ID: (Rabbit) 100009430, (Pig) 397358, (Human) 6550, (Mouse) 105243, (Rat) 24784
regulation of sodium ion transport
ion transport
receptor-mediated endocytosis
circadian rhythm
response to glucocorticoid
regulation of intracellular pH
potassium ion transmembrane transport
sodium ion import across plasma membrane
hydrogen ion transmembrane transport
sodium ion transport
regulation of pH
sodium ion transmembrane transport
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